(Q40675429)

22 September 2017

title

Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system (English)

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22 September 2017

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Carl Rosenblad

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22 September 2017

Biljana Georgievska

series ordinal

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22 September 2017

Deniz Kirik

series ordinal

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22 September 2017

language of work or name

English

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publication date

1 January 2003

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European Journal of Neuroscience

22 September 2017

published in

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22 September 2017

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22 September 2017

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22 September 2017

page(s)

260-270

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GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis

22 September 2017

cites work

1 reference

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Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

21 January 2018

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Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

21 January 2018

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Parkinson disease gene therapy moves toward the clinic

21 January 2018

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Differential regulation of neuropeptide mRNA expression in intrastriatal striatal transplants by host dopaminergic afferents

21 January 2018

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DA uptake sites, D1 and D2 receptors, D2 and preproenkephalin mRNAs and Fos immunoreactivity in rat striatal subregions after partial dopaminergic degeneration

21 January 2018

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Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity

21 January 2018

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Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector

21 January 2018

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Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease

21 January 2018

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Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo.

21 January 2018

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Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat.

21 January 2018

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Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor

21 January 2018

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Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

21 January 2018

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Glial cell line-derived neurotrophic factor prevents death, but not reductions in tyrosine hydroxylase, of injured nigrostriatal neurons in adult rats

21 January 2018

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Intranigral or intrastriatal injections of GDNF: effects on monoamine levels and behavior in rats

21 January 2018

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Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease

21 January 2018

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Immunochemical analysis of dopamine transporter protein in Parkinson's disease

21 January 2018

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Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution

21 January 2018

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In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin

21 January 2018

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Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model.

21 January 2018

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Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.

21 January 2018

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Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion

21 January 2018

1 reference

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Increase of proenkephalin mRNA and enkephalin content of rat striatum after daily injection of haloperidol for 2 to 3 weeks

21 January 2018

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Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

21 January 2018

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GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons

21 January 2018

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Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

21 January 2018

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Neurotransmitter-related gene expression in intrastriatal striatal transplants. III. Regulation by host cortical and dopaminergic afferents

21 January 2018

1 reference

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TH protein and mRNA in nigrostriatal dopaminergic neurons are down-regulated by continuous but not intermittent apomorphine

21 January 2018

1 reference

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Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral

21 January 2018

1 reference

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10.1046/J.1460-9568.2003.02456.X

21 January 2018

Identifiers

DOI

1 reference

22 September 2017

1 reference