(Q40533711)

21 September 2017

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title

Altered DNA topoisomerase II in multidrug resistance (English)

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21 September 2017

main subject

multiple drug resistance

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W T Beck

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21 September 2017

M K Danks

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21 September 2017

J S Wolverton

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21 September 2017

B Granzen

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21 September 2017

M Chen

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21 September 2017

C A Schmidt

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21 September 2017

B Y Bugg

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21 September 2017

E Friche

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21 September 2017

D P Suttle

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21 September 2017

publication date

1 January 1993

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21 September 2017

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21 September 2017

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21 September 2017

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21 September 2017

page(s)

115-119

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Expression of a mutant DNA topoisomerase II in CCRF-CEM human leukemic cells selected for resistance to teniposide

21 September 2017

cites work

1 reference

12 December 2020

Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26.

1 reference

12 December 2020

Cloning and characterization of the 5'-flanking region of the human topoisomerase II alpha gene

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12 December 2020

Increased phosphorylation of DNA topoisomerase II in etoposide-resistant mutants of human cancer KB cells

1 reference

12 December 2020

In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II. Cell cycle analysis.

1 reference

12 December 2020

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

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12 December 2020

Increased ATP requirement for activity of and complex formation by DNA topoisomerase II from human leukemic CCRF-CEM cells selected for resistance to teniposide

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12 December 2020

Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression

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12 December 2020

Atypical multiple drug resistance in a human leukemic cell line selected for resistance to teniposide (VM-26).

1 reference

12 December 2020

Purification and characterization of an altered topoisomerase II from a drug-resistant Chinese hamster ovary cell line.

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12 December 2020

Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively

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12 December 2020

Purification of topoisomerase II from amsacrine-resistant P388 leukemia cells. Evidence for two forms of the enzyme

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12 December 2020

Decreased DNA topoisomerase II in daunorubicin-resistant Ehrlich ascites tumor cells

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12 December 2020

Identification of a point mutation in the topoisomerase II gene from a human leukemia cell line containing an amsacrine-resistant form of topoisomerase II

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12 December 2020

Phosphorylation of DNA topoisomerase II in a human tumor cell line

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12 December 2020

Two independent amsacrine-resistant human myeloid leukemia cell lines share an identical point mutation in the 170 kDa form of human topoisomerase II

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12 December 2020

Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA.

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12 December 2020

Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells.

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12 December 2020

Altered expression and transcription of the topoisomerase II gene in nitrogen mustard-resistant human cells.

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12 December 2020

Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22

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12 December 2020

Mechanisms of resistance to drugs that inhibit DNA topoisomerases

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12 December 2020

A homogeneous type II DNA topoisomerase from HeLa cell nuclei

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12 December 2020

Mitoxantrone resistance in HL-60 leukemia cells: reduced nuclear topoisomerase II catalytic activity and drug-induced DNA cleavage in association with reduced expression of the topoisomerase II beta isoform

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12 December 2020

DNA topoisomerase II immunostaining in human leukemia and rhabdomyosarcoma cell lines and their responses to topoisomerase II inhibitors

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12 December 2020

Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells

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12 December 2020

Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes

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12 December 2020

Single-strand conformational polymorphism analysis of the M(r) 170,000 isozyme of DNA topoisomerase II in human tumor cells

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12 December 2020

Experimental studies on biochemical modulation targeting topoisomerase I and II in human tumor xenografts in nude mice

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12 December 2020

Identifiers

DOI

10.1007/BF00749000

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Dimensions Publication ID

21 September 2017

1039828907

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