(Q40595058)

21 September 2017

title

Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway (English)

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21 September 2017

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21 September 2017

Douglas A. Lauffenburger

series ordinal

object named as

Douglas A Lauffenburger

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21 September 2017

Akihiro Iwabu

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21 September 2017

Kirsty Smith

series ordinal

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21 September 2017

Fred D Allen

series ordinal

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21 September 2017

language of work or name

English

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publication date

27 January 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

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21 September 2017

page(s)

14551-14560

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Cell migration: a physically integrated molecular process

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways

21 January 2018

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Cutting to the chase: calpain proteases in cell motility

21 January 2018

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Actin-based cell motility and cell locomotion

21 January 2018

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Differential localization of cytoplasmic myosin II isoforms A and B in avian interphase and dividing embryonic and immortalized cardiomyocytes and other cell types in vitro.

21 January 2018

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Fluorescence anisotropy imaging microscopy maps calmodulin binding during cellular contraction and locomotion

21 January 2018

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Specific Localization of Serine 19 Phosphorylated Myosin II during Cell Locomotion and Mitosis of Cultured Cells

21 January 2018

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Myosin light chain phosphatase: subunit composition, interactions and regulation

21 January 2018

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Dedicated myosin light chain kinases with diverse cellular functions

21 January 2018

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Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II.

21 January 2018

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Regulation of cell motility by mitogen-activated protein kinase

21 January 2018

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ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxis

21 January 2018

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Molecular mechanisms of nonmuscle myosin-II regulation

21 January 2018

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A negative feedback loop attenuates EGF-induced morphological changes

21 January 2018

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Mitogenic signaling from the egf receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism

21 January 2018

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Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

21 January 2018

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Protein kinase C delta (PKC delta): activation mechanisms and functions

21 January 2018

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

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Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms.

21 January 2018

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Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

21 January 2018

1 reference

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Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha.

21 January 2018

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Regulation of novel protein kinase C epsilon by phosphorylation.

21 January 2018

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Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex

21 January 2018

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Multiple pathways control protein kinase C phosphorylation

21 January 2018

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Requirements of protein kinase cdelta for catalytic function. Role of glutamic acid 500 and autophosphorylation on serine 643

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311981200

Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Rottlerin, a novel protein kinase inhibitor

21 January 2018

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Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement

21 January 2018

1 reference

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Ligand-induced transformation by a noninternalizing epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

A role of the C-terminal region of human Rad9 (hRad9) in nuclear transport of the hRad9 checkpoint complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

21 January 2018

1 reference

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Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cdelta tyrosine phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311981200

Biophysical integration of effects of epidermal growth factor and fibronectin on fibroblast migration

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311981200

Distribution of gelsolin and phosphoinositol 4,5-bisphosphate in lamellipodia during EGF-induced motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Directional motility induced by epidermal growth factor requires Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

How is actin polymerization nucleated in vivo?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

The cytoskeleton, cellular motility and the reductionist agenda.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Rho family proteins: coordinating cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Calpain cleaves RhoA generating a dominant-negative form that inhibits integrin-induced actin filament assembly and cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Rocks: multifunctional kinases in cell behaviour

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311981200

MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Regulation of Cell Migration by the Calcium-dependent Protease Calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Activation of m-calpain (calpain II) by epidermal growth factor is limited by protein kinase A phosphorylation of m-calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Protein kinase C-catalyzed phosphorylation of an inhibitory phosphoprotein of myosin phosphatase is involved in human platelet secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Protein kinase Calpha negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

Protein kinases C-gamma and -delta are involved in insulin-like growth factor I-induced migration of colonic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

The phosphoinositide-dependent kinase, PDK-1, phosphorylates conventional protein kinase C isozymes by a mechanism that is independent of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311981200

21 January 2018

Identifiers

DOI

10.1074/JBC.M311981200

1 reference

21 September 2017

1 reference