(Q40542542)

21 September 2017

title

Beta-secretase BACE1 is differentially controlled through muscarinic acetylcholine receptor signaling (English)

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21 September 2017

Thole Züchner

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21 September 2017

J Regino Perez-Polo

series ordinal

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21 September 2017

Reinhard Schliebs

series ordinal

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21 September 2017

publication date

1 July 2004

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Journal of Neuroscience Research

21 September 2017

published in

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21 September 2017

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21 September 2017

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21 September 2017

page(s)

250-257

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Expression of beta-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology

21 September 2017

cites work

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Muscarine enhances soluble amyloid precursor protein secretion in human neuroblastoma SH-SY5Y by a pathway dependent on protein kinase C(alpha), src-tyrosine kinase and extracellular signal-regulated kinase but not phospholipase C.

21 January 2018

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WAL 2014--a muscarinic agonist with preferential neuron-stimulating properties

21 January 2018

1 reference

The effect of the selective reversible acetylcholinesterase inhibitor E2020 on extracellular acetylcholine and biogenic amine levels in rat cortex

21 January 2018

1 reference

BACE1 (beta-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes

21 January 2018

1 reference

Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes

21 January 2018

1 reference

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

21 January 2018

1 reference

Cloning and expression of the rat BACE1 promoter.

21 January 2018

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Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

21 January 2018

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Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells

21 January 2018

1 reference

Regulation of β-amyloid precursor protein and inositol 1,4,5-trisphosphate receptor gene expression during differentiation of a human neuronal cell line

21 January 2018

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Role of neurotransmission in the regulation of amyloid beta-protein precursor processing

21 January 2018

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Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase

21 January 2018

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3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy

21 January 2018

1 reference

Role of protein kinase Calpha in the regulated secretion of the amyloid precursor protein

21 January 2018

1 reference

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

21 January 2018

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Inhibition of depolarisation-evoked [(3)H]noradrenaline release from SH-SYFY human neuroblastoma cells by muscarinic (M1) receptors is not mediated by changes in [Ca(2+)].

21 January 2018

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Cerebrospinal fluid cholinesterases--markers for loss of cholinergic basal forebrain neurons?

21 January 2018

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Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease

21 January 2018

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

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Oxidative stress increases expression and activity of BACE in NT2 neurons

21 January 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

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The regulation of neurotransmitter secretion by protein kinase C.

21 January 2018

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A unique regulatory profile and regional distribution of [3H]pirenzepine binding in the rat provide evidence for distinct M1 and M2 muscarinic receptor subtypes

21 January 2018

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

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Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JNR.20152

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release_lsr7mn3hjfhspmnih3q253usvq

21 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/lsr7mn3hjfhspmnih3q253usvq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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