(Q40384735)

20 September 2017

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title

William L. McGuire Memorial Symposium. Drug resistance to tamoxifen during breast cancer therapy (English)

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20 September 2017

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V C Jordan

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20 September 2017

D M Wolf

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20 September 2017

language of work or name

English

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publication date

1 January 1993

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Breast Cancer Research and Treatment

20 September 2017

published in

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20 September 2017

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20 September 2017

issue

1-2

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20 September 2017

page(s)

27-40

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Estrogen and antiestrogen resistance in human breast cancer cell lines

20 September 2017

cites work

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12 December 2020

Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo.

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12 December 2020

An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol

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12 December 2020

Characterization of a receptor-negative, hormone-nonresponsive clone derived from a T47D human breast cancer cell line kept under estrogen-free conditions

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12 December 2020

Point mutation of estrogen receptor (ER) in the ligand-binding domain changes the pharmacology of antiestrogens in ER-negative breast cancer cells stably expressing complementary DNAs for ER.

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12 December 2020

Resistance to tamoxifen with persisting sensitivity to estrogen: possible mediation by excessive antiestrogen binding site activity

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12 December 2020

Isolation and characterization of a tamoxifen-resistant cell line derived from MCF-7 human breast cancer cells

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12 December 2020

Variant human breast tumor estrogen receptor with constitutive transcriptional activity

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12 December 2020

Estrogen-like effects of tamoxifen on human endometrial carcinoma transplanted into nude mice

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12 December 2020

Investigation of the mechanism of tamoxifen-stimulated breast tumor growth with nonisomerizable analogues of tamoxifen and metabolites.

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12 December 2020

Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: high affinity for progestagenic and estrogenic steroids

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12 December 2020

Potential role of tamoxifen in prevention of breast cancer

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12 December 2020

Estradiol-stimulated growth of MCF-7 tumors implanted in athymic mice: a model to study the tumoristatic action of tamoxifen

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12 December 2020

Synthesis and estrogen receptor binding of 6,7-dihydro-8-phenyl-9-[4-[2-(dimethylamino)ethoxy] phenyl]-5H-benzocycloheptene, a nonisomerizable analogue of tamoxifen. X-ray crystallographic studies.

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12 December 2020

Role of hormones in the growth and regression of human breast cancer cells (MCF-7) transplanted into athymic nude mice

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12 December 2020

Estrogen receptor variants in clinical breast cancer

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12 December 2020

Characterization of the estrogen receptor in two antiestrogen-resistant cell lines, LY2 and T47D.

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12 December 2020

Stimulatory effects of antiandrogens on LNCaP human prostate tumor cell growth, EGF-receptor level and acid phosphatase secretion

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12 December 2020

The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

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12 December 2020

Transfection of v-rasH DNA into MCF-7 human breast cancer cells bypasses dependence on estrogen for tumorigenicity

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12 December 2020

Identification of estrogenic tamoxifen metabolite(s) in tamoxifen-resistant human breast tumors

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12 December 2020

Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor

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12 December 2020

Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration

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12 December 2020

Differential ability of antiestrogens to stimulate breast cancer cell (MCF-7) growth in vivo and in vitro

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12 December 2020

Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors

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12 December 2020

Hormone receptor assays: clinical usefulness in the management of carcinoma of the breast

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12 December 2020

Selection and characterization of a breast cancer cell line resistant to the antiestrogen LY 117018.

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12 December 2020

A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity

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12 December 2020

Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Early Breast Cancer Trialists' Collaborative Group

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12 December 2020

Influence of the antioestrogen tamoxifen on normal breast tissue

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12 December 2020

Estradiol-independent growth of a subline of MCF-7 human breast cancer cells in culture

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12 December 2020

Aberrant response in vitro of hormone-responsive prostate cancer cells to antiandrogens

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12 December 2020

Reversible control of oestradiol-stimulated growth of MCF-7 tumours by tamoxifen in the athymic mouse

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12 December 2020

Tamoxifen metabolites in patients on long-term adjuvant therapy for breast cancer

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12 December 2020

Characterisation of a tamoxifen-resistant variant of the ZR-75-1 human breast cancer cell line (ZR-75-9a1) and ability of the resistant phenotype

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12 December 2020

Tamoxifen and the isomers of 4-hydroxytamoxifen in tamoxifen-resistant tumors from breast cancer patients

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12 December 2020

Structure-function relationships of hydroxylated metabolites of tamoxifen that control the proliferation of estrogen-responsive T47D breast cancer cells in vitro.

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12 December 2020

Characterization of estrogen receptor variant mRNAs from human breast cancers

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12 December 2020

Gynecologic complications associated with long-term adjuvant tamoxifen therapy for breast cancer

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12 December 2020

Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens.

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12 December 2020

The proliferative effect of "anti-androgens" on the androgen-sensitive human prostate tumor cell line LNCaP.

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12 December 2020

Clinical significance of tamoxifen withdrawal response

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12 December 2020

Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice

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12 December 2020

Comparative study of Harvey-ras oncogene expression with conventional clinicopathologic parameters of breast cancer

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12 December 2020

Tamoxifen-induced tumor stimulation and withdrawal response

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12 December 2020

Endocrine therapy for advanced breast cancer: a review

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12 December 2020

Variant estrogen receptor mRNA species detected in human breast cancer biopsy samples.

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12 December 2020

Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse

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12 December 2020

Acquired tamoxifen resistance: correlation with reduced breast tumor levels of tamoxifen and isomerization of trans-4-hydroxytamoxifen.

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12 December 2020

Human breast cancer in the athymic nude mouse: cytostatic effects of long-term antiestrogen therapy

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12 December 2020

Independent molecular pathways in initiation and loss of hormone responsiveness of breast carcinomas.

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12 December 2020

Abnormal estrogen receptor in clinical breast cancer

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12 December 2020

Proliferation, hormonal responsiveness, and estrogen receptor content of MCF-7 human breast cancer cells grown in the short-term and long-term absence of estrogens

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12 December 2020

T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance.

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12 December 2020

Cellular and molecular events in loss of estrogen sensitivity in ZR-75-1 and T-47-D human breast cancer cells.

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12 December 2020

Adaptation of estrogen-dependent MCF-7 cells to low estrogen (phenol red-free) culture

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12 December 2020

Identifiers

DOI

10.1007/BF00683191

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Dimensions Publication ID

20 September 2017

1033038323

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