(Q40365717)

English

Both microtubule-stabilizing and microtubule-destabilizing drugs inhibit hypoxia-inducible factor-1alpha accumulation and activity by disrupting microtubule function.

scientific article published on October 2005

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Both microtubule-stabilizing and microtubule-destabilizing drugs inhibit hypoxia-inducible factor-1alpha accumulation and activity by disrupting microtubule function (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Erik R Kline

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Paraskevi Giannakakou

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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publication date

1 October 2005

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

65

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

19

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

9021-9028

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Microtubules and signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vincristine revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mRNA localization: message on the move

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia: the tumor's gateway to progression along the angiogenic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia as a target for combined modality treatments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen sensors and angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction to hypoxia-inducible factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of tumor hypoxia and anemia on radiation therapy outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting HIF-1 for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The taxanes: toxicity and quality of life considerations in advanced ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting topoisomerase I to inhibit hypoxia inducible factor 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proceedings of the Oxygen Homeostasis/Hypoxia Meeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epothilones: mechanism of action and biologic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxane-platinum combinations in advanced non-small cell lung cancer: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic review of taxane-containing versus non-taxane-containing regimens for adjuvant and neoadjuvant treatment of early breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploitation of the HIF axis for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of mRNA and eIF-2 alpha with the cytoskeleton in cells lacking vimentin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunofluorescent localization of protein synthesis components in mouse embryo fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translational initiation factor and ribosome association with the cytoskeletal framework fraction from HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of a Mr 50,000 cap-binding protein with the cytoskeleton in baby hamster kidney cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cells at intermediate oxygen levels can be more important than the "hypoxic fraction" in determining tumor response to fractionated radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubules and actin filaments: dynamic targets for cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of hypoxia inducible factor-1alpha in rat and human prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16204076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-04-4095

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16204076%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

ResearchGate publication ID

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