(Q40227628)

18 September 2017

title

Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia (English)

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18 September 2017

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R S Bindra

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18 September 2017

P M Glazer

series ordinal

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18 September 2017

language of work or name

English

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publication date

25 September 2006

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18 September 2017

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18 September 2017

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18 September 2017

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18 September 2017

page(s)

2048-2057

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The E2F family: specific functions and overlapping interests

18 September 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210001

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Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.

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Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells

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Emerging roles for E2F: Beyond the G1/S transition and DNA replication

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gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

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Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130.

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p107 and p130: versatile proteins with interesting pockets

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Pocket proteins and cell cycle control

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A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs

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Genotoxic stress induces expression of E2F4, leading to its association with p130 in prostate carcinoma cells.

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

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A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130

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Hypoxia links ATR and p53 through replication arrest

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Hypoxia--a key regulatory factor in tumour growth

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Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes

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Differential regulation of expression of the mammalian DNA repair genes by growth stimulation

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HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

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HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.

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Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells

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Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells

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Differential regulation of E2F1 apoptotic target genes in response to DNA damage.

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Rapid dephosphorylation of p107 following UV irradiation.

21 January 2018

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Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

21 January 2018

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The identification of E2F1-specific target genes

21 January 2018

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Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells

21 January 2018

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E2Fs link the control of G1/S and G2/M transcription

21 January 2018

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Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1210001

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Dimensions Publication ID

18 September 2017

1031360725

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