(Q40268739)

19 September 2017

title

Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum (English)

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19 September 2017

main subject

Dictyostelium discoideum

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Alfred Wittinghofer

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19 September 2017

Ineke Keizer-Gunnink

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19 September 2017

Arjan Kortholt

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19 September 2017

Holger Rehmann

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19 September 2017

Helmut Kae

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19 September 2017

Leonard Bosgraaf

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19 September 2017

Gerald Weeks

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19 September 2017

Peter J M Van Haastert

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19 September 2017

language of work or name

English

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publication date

12 June 2006

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Journal of Biological Chemistry

19 September 2017

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inferred from page(s)

published in

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19 September 2017

volume

281

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19 September 2017

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19 September 2017

page(s)

23367-23376

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All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Rap1 signalling: adhering to new models

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600804200

Linking Rap to cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

The GTPase superfamily: conserved structure and molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Dictyostelium: an ideal organism for genetic dissection of Ras signalling networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Small GTPases in Dictyostelium: lessons from a social amoeba

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600804200

The genome of the social amoeba Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

A novel Dictyostelium RasGEF required for chemotaxis and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

A novel Dictyostelium RasGEF is required for normal endocytosis, cell motility and multicellular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Identification of four candidate cGMP targets in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Roc, a Ras/GTPase domain in complex proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Chemoattractant-induced Ras activation during Dictyostelium aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Overexpression of an activated rasG gene during growth blocks the initiation of Dictyostelium development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

SadA, a novel adhesion receptor in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Dictyostelium RasG is required for normal motility and cytokinesis, but not growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

A Ras subfamily GTPase shows cell cycle-dependent nuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Evidence for a role for the Dictyostelium Rap1 in cell viability and the response to osmotic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

The small Mr Ras-like GTPase Rap1 and the phospholipase C pathway act to regulate phagocytosis in Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Talin-null cells of Dictyostelium are strongly defective in adhesion to particle and substrate surfaces and slightly impaired in cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

A novel phosphatidylinositol 4,5-bisphosphate-binding domain targeting the Phg2 kinase to the membrane in Dictyostelium cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

ARAP3 is a PI3K- and rap-regulated GAP for RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600804200

21 January 2018

Identifiers

DOI

10.1074/JBC.M600804200

1 reference

19 September 2017

1 reference