(Q40139360)

17 September 2017

title

Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins (English)

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17 September 2017

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Martin H Groschup

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17 September 2017

Hermann Schätzl

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17 September 2017

Elke Maas

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17 September 2017

Markus Geissen

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17 September 2017

Romina Rost

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17 September 2017

Takashi Onodera

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17 September 2017

Ina M Vorberg

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17 September 2017

language of work or name

English

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publication date

27 April 2007

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Journal of Biological Chemistry

17 September 2017

published in

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17 September 2017

volume

282

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17 September 2017

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17 September 2017

page(s)

18702-18710

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Mammalian prion biology: one century of evolving concepts

17 September 2017

cites work

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Synthetic mammalian prions

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Trafficking, turnover and membrane topology of PrP.

21 January 2018

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Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state

21 January 2018

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Mice devoid of PrP are resistant to scrapie

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Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.

21 January 2018

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Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

21 January 2018

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Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers

21 January 2018

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Dominant-negative inhibition of prion replication in transgenic mice

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Molecular distinction between pathogenic and infectious properties of the prion protein

21 January 2018

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Anchorless prion protein results in infectious amyloid disease without clinical scrapie

21 January 2018

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PrP knock-out and PrP transgenic mice in prion research

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Scrapie associated PrP accumulation and its prevention: insights from cell culture

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Prion strain-dependent differences in conversion of mutant prion proteins in cell culture

21 January 2018

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Multiple amino acid residues within the rabbit prion protein inhibit formation of its abnormal isoform

21 January 2018

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Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

21 January 2018

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Deletion of beta-strand and alpha-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform

21 January 2018

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Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

21 January 2018

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Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.

21 January 2018

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Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein

21 January 2018

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Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents

21 January 2018

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PrP polymorphisms tightly control sheep prion replication in cultured cells

21 January 2018

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Prions prevent neuronal cell-line death.

21 January 2018

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Overcoming interference to retroviral superinfection results in amplified expression and transmission of cloned genes

21 January 2018

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Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production

21 January 2018

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Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

21 January 2018

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Charged bipolar suramin derivatives induce aggregation of the prion protein at the cell surface and inhibit PrPSc replication

21 January 2018

1 reference

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Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Acute formation of protease-resistant prion protein does not always lead to persistent scrapie infection in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Prion infection impairs the cellular response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Cells release prions in association with exosomes

21 January 2018

1 reference

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Transfer of scrapie prion infectivity by cell contact in culture

21 January 2018

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Efficient dissemination of prions through preferential transmission to nearby cells.

21 January 2018

1 reference

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The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis

21 January 2018

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21 January 2018

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Prion propagation in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

A change in the conformation of prions accompanies the emergence of a new prion strain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

NMR structure of the mouse prion protein domain PrP(121-231)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

NMR characterization of the full‐length recombinant murine prion protein, mPrP(23–231)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Prion protein NMR structures of cats, dogs, pigs, and sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Structural studies of the scrapie prion protein by electron crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Evidence for assembly of prions with left-handed beta-helices into trimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Two-rung Model of a Left-handed β-Helix for Prions Explains Species Barrier and Strain Variation in Transmissible Spongiform Encephalopathies

21 January 2018

1 reference

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Beta-sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

The charge structure of helix 1 in the prion protein regulates conversion to pathogenic PrPSc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Prion protein NMR structure and species barrier for prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Purification and properties of the cellular and scrapie hamster prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Toward molecular dissection of PrPC-PrPSc interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

Three-dimensional NMR structure of a self-folding domain of the prion protein PrP(121–231)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701309200

21 January 2018

Identifiers

DOI

10.1074/JBC.M701309200

1 reference

17 September 2017

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