(Q40142846)

17 September 2017

title

Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis (English)

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17 September 2017

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Yue-Wei Qian

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17 September 2017

Robert J Schmidt

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17 September 2017

Youyan Zhang

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17 September 2017

Shaoyou Chu

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17 September 2017

Aimin Lin

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17 September 2017

He Wang

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17 September 2017

Xiliang Wang

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17 September 2017

Thomas P Beyer

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17 September 2017

William R Bensch

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17 September 2017

Weiming Li

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17 September 2017

Mariam E Ehsani

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17 September 2017

Deshun Lu

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17 September 2017

Robert J Konrad

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17 September 2017

Patrick I Eacho

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17 September 2017

David E Moller

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17 September 2017

Sotirios K Karathanasis

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17 September 2017

Guoqing Cao

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17 September 2017

publication date

20 April 2007

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Journal of Lipid Research

17 September 2017

published in

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17 September 2017

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17 September 2017

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17 September 2017

page(s)

1488-1498

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The IDEAL cholesterol: lower is better

17 September 2017

cites work

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Can low-density lipoprotein be too low? The safety and efficacy of achieving very low low-density lipoprotein with intensive statin therapy: a PROVE IT-TIMI 22 substudy

21 January 2018

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21 January 2018

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

21 January 2018

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Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

21 January 2018

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A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree

21 January 2018

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Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia

21 January 2018

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Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

21 January 2018

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Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

21 January 2018

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A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

21 January 2018

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Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy

21 January 2018

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Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote

21 January 2018

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Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

21 January 2018

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The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

21 January 2018

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Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells

21 January 2018

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Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

21 January 2018

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Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

21 January 2018

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Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

21 January 2018

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NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

21 January 2018

1 reference

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Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice

21 January 2018

1 reference

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Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

21 January 2018

1 reference

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10.1194/JLR.M700071-JLR200

21 January 2018

Identifiers

DOI

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17 September 2017

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