(Q40054476)

16 September 2017

title

GSK-3beta inhibition enhances sorafenib-induced apoptosis in melanoma cell lines (English)

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16 September 2017

David J Panka

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16 September 2017

Daniel C Cho

series ordinal

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16 September 2017

Michael B Atkins

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16 September 2017

James W Mier

series ordinal

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16 September 2017

language of work or name

English

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publication date

8 November 2007

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Journal of Biological Chemistry

16 September 2017

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inferred from page(s)

published in

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16 September 2017

volume

283

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16 September 2017

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16 September 2017

page(s)

726-732

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The Raf inhibitor BAY 43-9006 (Sorafenib) induces caspase-independent apoptosis in melanoma cells

16 September 2017

cites work

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The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.

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Structural insights into the degradation of Mcl-1 induced by BH3 domains

21 January 2018

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 January 2018

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Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

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Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

21 January 2018

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Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

21 January 2018

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The glamour and gloom of glycogen synthase kinase-3

21 January 2018

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Glycogen synthase kinase-3: properties, functions, and regulation

21 January 2018

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Glycogen synthase kinase-3 beta is highly activated in nuclei and mitochondria

21 January 2018

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Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta

21 January 2018

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Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3beta and Shaggy.

21 January 2018

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Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity

21 January 2018

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A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function

21 January 2018

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Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells

21 January 2018

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An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells

21 January 2018

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Mutations of the BRAF gene in human cancer

21 January 2018

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Rapid evolution of the human gene for cytochrome c oxidase subunit IV

21 January 2018

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The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism

21 January 2018

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

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Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity

21 January 2018

1 reference

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Chromosome alignment and segregation regulated by ubiquitination of survivin

21 January 2018

1 reference

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Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells

21 January 2018

1 reference

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Multisite phosphorylation of glycogen synthase

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M705343200

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16 September 2017

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