(Q57976952)

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Mutational Analysis of the Predicted First Transmembrane Segment of Each Homologous Half of Human P-glycoprotein Suggests That They Are Symmetrically Arranged in the Membrane

scientific article published in Journal of Biological Chemistry

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

Mutational analysis of the predicted first transmembrane segment of each homologous half of human P-glycoprotein suggests that they are symmetrically arranged in the membrane (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

transmembrane protein

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mutational analysis

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based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

author name string

D M Clarke

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

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1 June 1996

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

271

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

26

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

15414-15419

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

Multidrug resistance protein (Mdr)-alkaline phosphatase hybrids in Escherichia coli suggest a major revision in the topology of the C-terminal half of Mdr.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

The biochemistry of P-glycoprotein-mediated multidrug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Mutations to amino acids located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Topological determinants of internal transmembrane segments in P-glycoprotein sequences.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Membrane topology of a cysteine-less mutant of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Alternate translation initiation codons can create functional forms of cystic fibrosis transmembrane conductance regulator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Novel pore-lining residues in CFTR that govern permeation and open-channel block

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.26.15414

21 January 2018

Identifiers

10.1074/JBC.271.26.15414

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663176%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

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