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(Q56508014)
English
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
scientific article published on 01 October 2001
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
title
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
main subject
telomere length
0 references
author
Margaret A Strong
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Carol Greider
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
M T Hemann
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
L Y Hao
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
language of work or name
English
0 references
publication date
1 October 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
107
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
67-77
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
cites work
Telomere length predicts replicative capacity of human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere states and cell fates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replicative senescence and cell immortality: the role of telomeres and telomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of telomerase in a human tumor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Robertsonian metacentrics of the house mouse lose telomeric sequences but retain some minor satellite DNA in the pericentromeric area
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pericentromeric organization at the fusion point of mouse Robertsonian translocation chromosomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere length regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian telomeres end in a large duplex loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere dysfunction increases mutation rate and genomic instability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere length, telomere-binding proteins, and DNA damage signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere dysfunction triggers developmentally regulated germ cell apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse minor satellite DNA genetically maps to the centromere and is physically linked to the proximal telomere
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Block in anaphase chromosome separation caused by a telomerase template mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repair of telomeric DNA prior to replicative senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterogeneity in telomere length of human chromosomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of mouse telomerase in highly proliferative organs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic instabilities in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multicolour spectral karyotyping of mouse chromosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Short telomeres on human chromosome 17p
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of short telomeres in human fibroblasts prior to replicative senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reprogramming of Telomerase by Expression of Mutant Telomerase RNA Template in Human Cells Leads to Altered Telomeres That Correlate with Reduced Cell Viability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Behavior in Successive Nuclear Divisions of a Chromosome Broken at Meiosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Fusion of Broken Ends of Chromosomes Following Nuclear Fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Runaway telomere elongation caused by telomerase RNA gene mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Construction of a smallMus musculusrepetitive DNA library: identification of a new satedllite sequence inMus musculus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of telomere-length heterogeneity in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomeres and mechanisms of Robertsonian fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of telomere length by the human telomeric protein TRF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900504-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(01)00504-9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PubMed publication ID
11595186
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11595186
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11595186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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