(Q48338179)

10 February 2018

title

Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania (English)

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10 February 2018

Tiago Wilson Patriarca Mineo

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10 February 2018

Karina Bortoluci

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10 February 2018

Marcelo Torres Bozza

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10 February 2018

Dario S. Zamboni

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10 February 2018

Diego L Costa

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Vanessa Carregaro

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Maria Bellio

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Richard A Flavell

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10 February 2018

author name string

Djalma S Lima-Junior

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10 February 2018

Larissa D Cunha

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10 February 2018

Alexandre L N Silva

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10 February 2018

Fredy R S Gutierrez

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10 February 2018

João S Silva

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10 February 2018

language of work or name

English

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publication date

9 June 2013

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10 February 2018

published in

Nature Medicine

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10 February 2018

volume

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10 February 2018

issue

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10 February 2018

page(s)

909-915

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10 February 2018

Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis.

cites work

1 reference

12 December 2020

Cutaneous leishmaniasis

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12 December 2020

The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response

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12 December 2020

A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation

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12 December 2020

Resistance toLeishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages

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12 December 2020

Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-gamma-stimulated macrophages by induction of tumor necrosis factor-alpha

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12 December 2020

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

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12 December 2020

Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue

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12 December 2020

Subversion of host cell signalling by the protozoan parasite Leishmania.

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12 December 2020

Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria

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12 December 2020

Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?

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12 December 2020

Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes

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12 December 2020

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

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12 December 2020

CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells

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12 December 2020

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

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12 December 2020

Enhanced Th2-like responses in IL-1 type 1 receptor-deficient mice

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12 December 2020

Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis

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12 December 2020

Genetically Resistant Mice Lacking MyD88-Adapter Protein Display a High Susceptibility to Leishmania major Infection Associated with a Polarized Th2 Response

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12 December 2020

The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses

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12 December 2020

Immunopathology of experimental cutaneous leishmaniasis

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12 December 2020

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

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12 December 2020

Distinct innate and acquired immune responses to Leishmania in putative susceptible and resistant human populations endemically exposed to L. (Viannia) panamensis infection

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12 December 2020

Host cell signalling and leishmania mechanisms of evasion.

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12 December 2020

IL-1β (-511T/C) gene polymorphism not IL-1β (+3953T/C) and LT-α (+252A/G) gene variants confers susceptibility to visceral leishmaniasis.

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12 December 2020

Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major.

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12 December 2020

A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?

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12 December 2020

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

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12 December 2020

NOD-like receptors: role in innate immunity and inflammatory disease

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12 December 2020

A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity.

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12 December 2020

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

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12 December 2020

K+ efflux is required for histone H3 dephosphorylation by Listeria monocytogenes listeriolysin O and other pore-forming toxins

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12 December 2020

Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide

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12 December 2020

Cryopyrin activates the inflammasome in response to toxins and ATP

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12 December 2020

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

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12 December 2020

Nitric oxide: physiology, pathophysiology, and pharmacology

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12 December 2020

The inflammasomes: guardians of the body

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12 December 2020

Nitric oxide as a secretory product of mammalian cells

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12 December 2020

IL-1 signalling is dispensable for protective immunity in Leishmania-resistant mice

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12 December 2020

Disease severity in patients infected with Leishmania mexicana relates to IL-1β.

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12 December 2020

Modulation of dendritic cell function by Leishmania parasites

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12 December 2020

Nitrate synthesis in the germfree and conventional rat

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12 December 2020

Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts.

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12 December 2020

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.

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12 December 2020

Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism

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12 December 2020

Exploring the full spectrum of macrophage activation

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12 December 2020

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

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12 December 2020

The immunology of susceptibility and resistance to Leishmania major in mice

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12 December 2020

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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12 December 2020

A method for generation of bone marrow-derived macrophages from cryopreserved mouse bone marrow cells

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12 December 2020

Distinct roles for IL-1 receptor type I signaling in early versus established Leishmania major infections

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12 December 2020

High levels of susceptibility and T helper 2 response in MyD88-deficient mice infected with Leishmania major are interleukin-4 dependent

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12 December 2020

Identifiers

DOI

10.1038/NM.3221

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10 February 2018

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10 February 2018