(Q42155404)

17 October 2017

Diverse cell death pathways result from a single missense mutation in weaver mouse. (English)

1 reference

17 October 2017

A Migheli

1 reference

17 October 2017

R Piva

1 reference

17 October 2017

J Wei

1 reference

17 October 2017

A Attanasio

1 reference

17 October 2017

S Casolino

1 reference

17 October 2017

M E Hodes

1 reference

17 October 2017

S R Dlouhy

1 reference

17 October 2017

S A Bayer

1 reference

17 October 2017

B Ghetti

1 reference

17 October 2017

language of work or name

English

0 references

publication date

1 December 1997

1 reference

The American Journal of Pathology

17 October 2017

1 reference

17 October 2017

151

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17 October 2017

1 reference

17 October 2017

1629-1638

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Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.

17 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

The weaver mutation of GIRK2 results in a loss of inwardly rectifying K+ current in cerebellar granule cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Cell division and the nervous system: regulating the cycle from neural differentiation to death

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

In situ apoptotic cell labeling by the TUNEL method: improvement and evaluation on cell preparations

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Nonselective and G betagamma-insensitive weaver K+ channels

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

IRK(1-3) and GIRK(1-4) inwardly rectifying K+ channel mRNAs are differentially expressed in the adult rat brain

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

The molecular biology of apoptosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

The lysosomal system in neuronal cell death: a review

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Hypospermatogenesis is the cause of infertility in the male weaver mutant mouse

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Apoptosis in substantia nigra following developmental striatal excitotoxic injury

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Fluctuations and ultrastructural localization of oncoproteins and cell cycle regulatory proteins during growth and apoptosis of synchronized AGF cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Apoptosis, oncosis, and necrosis. An overview of cell death

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Ultrastructural detection of DNA strand breaks in apoptotic neural cells by in situ end-labelling techniques

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

A radical hypothesis for neurodegeneration

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Organization of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Abnormal rate of granule cell migration in the cerebellum of “weaver” mutant mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Mesencephalic dopamine cell deficit involves areas A8, A9 and A10 in weaver mutant mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Development and death of external granular layer cells in the weaver mouse cerebellum: a quantitative study

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Purkinje cell loss is due to a direct action of the weaver gene in Purkinje cells: evidence from chimeric mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Developmental cell death: morphological diversity and multiple mechanisms

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Programmed cell death. Electrophysiological and ultrastructural correlations in metamorphosing muscles of lepidopteran insects

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Cell death: programmed, apoptosis, necrosis, or other?

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Neuron death in the substantia nigra of weaver mouse occurs late in development and is not apoptotic

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Cell death in the midbrain of the murine mutation weaver.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Apoptosis in substantia nigra following developmental hypoxic-ischemic injury.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

The K+ channel inward rectifier subunits form a channel similar to neuronal G protein-gated K+ channel

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

DNA fragmentation and activation of c-Jun in the cerebellum of mutant mice (weaver, Purkinje cell degeneration).

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Microscale autoradiographic method for the qualitative and quantitative analysis of apoptotic DNA fragmentation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

The induction of multiple cell cycle events precedes target-related neuronal death

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

Dopamine deficiency in the weaver mutant mouse.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858371

The role of inducible transcription factors in apoptotic nerve cell death

17 August 2018

1 reference

12 December 2020

Detection of apoptosis in weaver cerebellum by electron microscopic in situ end-labeling of fragmented DNA

1 reference

12 December 2020

In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum

1 reference

12 December 2020

Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus

1 reference

12 December 2020

Degeneration of Sertoli and spermatogenic cells in homozygous and heterozygous weaver mice

1 reference

12 December 2020

Systematic differences in time of dopaminergic neuron origin between normal mice and homozygous weaver mutants

1 reference

12 December 2020

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

12 December 2020

Early postnatal changes of the dopaminergic mesencephalic neurons in the weaver mutant mouse

1 reference

12 December 2020

Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice

1 reference

12 December 2020

Ultrastructure of excitotoxic neuronal death in murine cortical culture

1 reference

12 December 2020

A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks

1 reference

12 December 2020

Identifiers

1 reference

17 October 2017

PubMed publication ID

9403713

1 reference