(Q37861631)

24 August 2017

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title

Cytotoxic immunotherapy strategies for cancer: mechanisms and clinical development (English)

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24 August 2017

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Laura K Aguilar

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24 August 2017

Brian W Guzik

series ordinal

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24 August 2017

Estuardo Aguilar-Cordova

series ordinal

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24 August 2017

language of work or name

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1 August 2011

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Journal of Cellular Biochemistry

24 August 2017

published in

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24 August 2017

volume

112

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24 August 2017

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24 August 2017

page(s)

1969-1977

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Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis

24 August 2017

cites work

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Cytopathic effect of in situ gene therapy in prostate cancer

21 January 2018

1 reference

Biological response determinants in HSV-tk + ganciclovir gene therapy for prostate cancer

21 January 2018

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Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors

21 January 2018

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Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir

21 January 2018

1 reference

Enhanced therapeutic effect of HSV-tk+GCV gene therapy and ionizing radiation for prostate cancer

21 January 2018

1 reference

Prostate carcinoma among men with human immunodeficiency virus infection

21 January 2018

1 reference

HMGB1 mediates endogenous TLR2 activation and brain tumor regression

21 January 2018

1 reference

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

21 January 2018

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Prostate cancer gene therapy: herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models

21 January 2018

1 reference

Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation

21 January 2018

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Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors.

21 January 2018

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Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma

21 January 2018

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The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro

21 January 2018

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Phase I trial of replication-competent adenovirus-mediated suicide gene therapy combined with IMRT for prostate cancer

21 January 2018

1 reference

Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer

21 January 2018

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Immune modulation by ionizing radiation and its implications for cancer immunotherapy

21 January 2018

1 reference

Sustained long-term immune responses after in situ gene therapy combined with radiotherapy and hormonal therapy in prostate cancer patients

21 January 2018

1 reference

Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: preliminary results of a phase I trial in patients with recurrent malignant gliomas.

21 January 2018

1 reference

Tumor-induced modulation of dendritic cell function

21 January 2018

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Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer

21 January 2018

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Immunosuppressive therapy and malignancy in organ transplant recipients: a systematic review

21 January 2018

1 reference

Adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy leads to systemic activity against spontaneous and induced metastasis in an orthotopic mouse model of prostate cancer

21 January 2018

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Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck.

21 January 2018

1 reference

Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study

21 January 2018

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Adenovirus-mediated thymidine kinase gene therapy in combination with topotecan for patients with recurrent ovarian cancer: 2.5-year follow-up.

21 January 2018

1 reference

Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study

21 January 2018

1 reference

In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial.

21 January 2018

1 reference

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

21 January 2018

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AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

21 January 2018

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Innate immune recognition

21 January 2018

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Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy

21 January 2018

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Adaptive immunity maintains occult cancer in an equilibrium state

21 January 2018

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Cancer gene therapy with HSV-tk/GCV system depends on T-cell-mediated immune responses and causes apoptotic death of tumor cells in vivo

21 January 2018

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Efficacy of repeated adenoviral suicide gene therapy in a localized murine tumor model

21 January 2018

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Roles of heat-shock proteins in antigen presentation and cross-presentation

21 January 2018

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Desirable cell death during anticancer chemotherapy

21 January 2018

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Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

21 January 2018

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The danger model: a renewed sense of self

21 January 2018

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Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression

21 January 2018

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Prostate-specific antigen response and systemic T cell activation after in situ gene therapy in prostate cancer patients failing radiotherapy

21 January 2018

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The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects.

21 January 2018

1 reference

Adenovirus-mediated gene therapy of experimental gliomas

21 January 2018

1 reference

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

21 January 2018

1 reference

Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma.

21 January 2018

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The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats

21 January 2018

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Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells

21 January 2018

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Migration of dendritic cell subsets and their precursors.

21 January 2018

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Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma

21 January 2018

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Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

21 January 2018

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Enhanced systemic T-cell activation after in situ gene therapy with radiotherapy in prostate cancer patients

21 January 2018

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Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells

21 January 2018

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Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir

21 January 2018

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Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy

21 January 2018

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In vivo surgical resection plus adjuvant gene therapy in the treatment of mammary and prostate cancer

21 January 2018

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Intratumoral adenovirus-mediated suicide gene transfer for hepatic metastases from colorectal adenocarcinoma: results of a phase I clinical trial

21 January 2018

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Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data

21 January 2018

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Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients

21 January 2018

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Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.

21 January 2018

1 reference

Virus specific immune responses after human neoadjuvant adenovirus-mediated suicide gene therapy for prostate cancer.

21 January 2018

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Generation of an anti-tumour immune response in a non-immunogenic tumour: HSVtk killing in vivo stimulates a mononuclear cell infiltrate and a Th1-like profile of intratumoural cytokine expression

21 January 2018

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Enhanced therapeutic effect of multiple injections of HSV-TK + GCV gene therapy in combination with ionizing radiation in a mouse mammary tumor model

21 January 2018

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Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance

21 January 2018

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Vaccines with enhanced costimulation maintain high avidity memory CTL.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCB.23126

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24 August 2017

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