(Q36076151)

12 August 2017

Etiopathogenesis of nonalcoholic steatohepatitis: role of obesity, insulin resistance and mechanisms of hepatotoxicity (English)

1 reference

12 August 2017

0 references

0 references

1 reference

1 reference

Praveen Guturu

1 reference

12 August 2017

Andrea Duchini

series ordinal

1 reference

12 August 2017

25 June 2012

1 reference

International Journal of Hepatology

12 August 2017

1 reference

12 August 2017

2012

1 reference

12 August 2017

212865

1 reference

Creative Commons Attribution 3.0 Unported

12 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

1 reference

April 2022 Public Data File from Crossref

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2 October 2017

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Apoptosis as a Mechanism for Liver Disease Progression

2 October 2017

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Do nutrient-gut-microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes?

2 October 2017

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A fresh look at NASH pathogenesis. Part 1: the metabolic movers.

2 October 2017

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2 October 2017

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Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

2 October 2017

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The sites and topology of mitochondrial superoxide production

2 October 2017

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Non-alcoholic fatty liver disease from pathogenesis to management: an update

2 October 2017

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Apoptosis and cytokines in non-alcoholic steatohepatitis

2 October 2017

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Role of insulin resistance and lipotoxicity in non-alcoholic steatohepatitis

2 October 2017

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Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome

2 October 2017

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Recent advances in understanding leptin signaling and leptin resistance

2 October 2017

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Lipotoxicity in nonalcoholic fatty liver disease: not all lipids are created equal

2 October 2017

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2 October 2017

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Hepatic lipid metabolism and non-alcoholic fatty liver disease.

2 October 2017

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Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential

2 October 2017

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How mitochondria produce reactive oxygen species

2 October 2017

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Mechanisms of disease progression in nonalcoholic fatty liver disease

2 October 2017

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Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease

2 October 2017

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Soft drink consumption linked with fatty liver in the absence of traditional risk factors

2 October 2017

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Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD).

2 October 2017

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Non-alcoholic fatty liver disease: an overview of prevalence, diagnosis, pathogenesis and treatment considerations

2 October 2017

1 reference

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Hepatic triglyceride synthesis and nonalcoholic fatty liver disease

2 October 2017

1 reference

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Fructose consumption as a risk factor for non-alcoholic fatty liver disease

2 October 2017

1 reference

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The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity

2 October 2017

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Endoplasmic reticulum stress and liver injury

2 October 2017

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Signal integration in the endoplasmic reticulum unfolded protein response

2 October 2017

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Obesity, Inflammation, and Insulin Resistance

2 October 2017

1 reference

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Adipocytokines: mediators linking adipose tissue, inflammation and immunity

2 October 2017

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Central nervous system control of food intake and body weight

2 October 2017

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Inflammation and insulin resistance

2 October 2017

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ER stress: can the liver cope?

2 October 2017

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Non alcoholic fatty liver disease: a clinical approach and review

2 October 2017

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

2 October 2017

1 reference

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The epidemiology of nonalcoholic fatty liver disease in adults

2 October 2017

1 reference

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Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Nonalcoholic fatty liver disease: from steatosis to cirrhosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

The natural history and risk factors for progression of non-alcoholic fatty liver disease and steatohepatitis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Review article: the metabolic syndrome and non-alcoholic fatty liver disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Apoptosis in alcoholic and nonalcoholic steatohepatitis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Inflammation, stress, and diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Role of a critical visceral adipose tissue threshold (CVATT) in metabolic syndrome: implications for controlling dietary carbohydrates: a review

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts

2 October 2017

1 reference

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N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?

2 October 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

2 October 2017

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The pathogenesis of nonalcoholic steatohepatitis and other fatty liver diseases: a four-step model including the role of lipid release and hepatic venular obstruction in the progression to cirrhosis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

An introduction to the molecular mechanisms of apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase, fasting insulin, and quality of life

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Obesity is associated with macrophage accumulation in adipose tissue

2 October 2017

1 reference

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The role of depot fat in the hypothalamic control of food intake in the rat.

2 October 2017

2 references

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2 October 2017

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Do regional differences in adipocyte biology provide new pathophysiological insights?

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

A central role for JNK in obesity and insulin resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

AGA technical review on nonalcoholic fatty liver disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

2 October 2017

1 reference

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The hormone resistin links obesity to diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Steatohepatitis: a tale of two "hits"?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Tumor necrosis factor alpha inhibits signaling from the insulin receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Long-term feeding of a synthetic diet rich in disaccharides induces hepatic fibrosis in nonalcoholic fatty liver disease in Zucker rats.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Role of body fat distribution in the decline in insulin sensitivity and glucose tolerance with age

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

High-fat diet: a trigger of non-alcoholic steatohepatitis? Preliminary findings in obese subjects

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Nutritional assessments of patients with non-alcoholic fatty liver disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

A lipidomic analysis of nonalcoholic fatty liver disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity?

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Plasma total and free fatty acids composition in human non-alcoholic steatohepatitis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Circulating tumor necrosis factor-alpha concentrations in a native Canadian population with high rates of type 2 diabetes mellitus

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389710

Toll-like receptor signaling and liver fibrosis

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F212865

Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F212865

The relation of body fat mass and distribution to markers of chronic inflammation

21 January 2018

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12 December 2020

Dietary habits and nutrient intake in non-alcoholic steatohepatitis

1 reference

12 December 2020

Natural history of NAFLD: remarkably benign in the absence of cirrhosis

1 reference

12 December 2020

On the Treatment of Glycosuria and Diabetes Mellitus with Sodium Salicylate

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12 December 2020

Death receptors in liver biology and pathobiology

1 reference

12 December 2020

Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis

1 reference

12 December 2020

1 reference

12 December 2020

In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease

1 reference

12 December 2020

A case-control study on nutritional risk factors in non-alcoholic fatty liver disease in Indian population

1 reference

12 December 2020

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

1 reference

12 December 2020

Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/212865

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22792473

1 reference