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A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization.

scientific article published on 29 October 2007

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scholarly article

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Europe PubMed Central

PMC publication ID

17 August 2017

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Europe PubMed Central

A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization. (English)

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Europe PubMed Central

PMC publication ID

17 August 2017

G protein-coupled receptor

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author name string

G Milligan

1

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Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

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publication date

29 October 2007

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Europe PubMed Central

PMC publication ID

17 August 2017

British Journal of Pharmacology

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Europe PubMed Central

PMC publication ID

17 August 2017

153 Suppl 1

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Europe PubMed Central

PMC publication ID

17 August 2017

S216-29

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Europe PubMed Central

PMC publication ID

17 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

A trafficking checkpoint controls GABA(B) receptor heterodimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Functional significance of oligomerization of G-protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

G-protein-coupled receptors function as oligomers in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

GABAB receptors - the first 7TM heterodimers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca(2+) receptor critical for dimerization. Implications for function of monomeric Ca(2+) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Characterization of the dimerization of metabotropic glutamate receptors using an N-terminal truncation of mGluR1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Heterodimerization is required for the formation of a functional GABA(B) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Dimerization of the lutropin receptor: insights from computational modeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

29 September 2017

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

27 June 2018

Specificity in transmembrane helix-helix interactions mediated by aromatic residues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Two transmembrane Cys residues are involved in 5-HT4 receptor dimerization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

BRET analysis of GPCR oligomerization: newer does not mean better

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Dimerization of the human melanocortin 1 receptor: functional consequences and dominant-negative effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Homo- and hetero-oligomerization of beta-arrestins in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

The identification of a minimal dimerization motif QXXS that enables homo- and hetero-association of transmembrane helices in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

G Protein activation without subunit dissociation depends on a G{alpha}(i)-specific region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

A constitutively active GPCR retains its G protein specificity and the ability to form dimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Prediction of interfaces for oligomerizations of G-protein coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Multiple interactions between transmembrane helices generate the oligomeric alpha1b-adrenoceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Oligomerization, Biogenesis, and Signaling Is Promoted by a Glycophorin A-like Dimerization Motif in Transmembrane Domain 1 of a Yeast G Protein-coupled Receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

C5a receptor oligomerization. I. Disulfide trapping reveals oligomers and potential contact surfaces in a G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

The intracellular loops of the GB2 subunit are crucial for G-protein coupling of the heteromeric gamma-aminobutyrate B receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268067

4 September 2018

Allosteric modulation of heterodimeric G-protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0707490

21 January 2018

Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: insights from computational analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dominant-negative human growth hormone-releasing hormone (GHRH) receptor splice variant inhibits GHRH binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computational prediction of homodimerization of the A3 adenosine receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor 5 is a disulfide-linked dimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesangial AT1/B2 receptor heterodimers contribute to angiotensin II hyperresponsiveness in experimental hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/17965750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0707490

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

0 references

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