(Q34357844)

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Inhibition of O-GlcNAcase in perfused rat hearts by NAG-thiazolines at the time of reperfusion is cardioprotective in an O-GlcNAc-dependent manner.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833964%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Inhibition of O-GlcNAcase in perfused rat hearts by NAG-thiazolines at the time of reperfusion is cardioprotective in an O-GlcNAc-dependent manner (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833964%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2

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13 February 2020

author name string

Boglarka Laczy

1

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13 February 2020

Charlye A Brocks

3

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13 February 2020

Istvan Wittmann

4

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13 February 2020

John C Chatham

5

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13 February 2020

publication date

10 September 2010

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13 February 2020

American Journal of Physiology Heart and Circulatory Physiology

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833964%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

299

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833964%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833964%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

H1715-27

1 reference

Europe PubMed Central

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13 February 2020

Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Cardiac preconditioning for ischaemia: lost in translation.

1 reference

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6 July 2018

Increased O-linked beta-N-acetylglucosamine levels on proteins improves survival, reduces inflammation and organ damage 24 hours after trauma-hemorrhage in rats

1 reference

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6 July 2018

O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Protein O-GlcNAcylation: a new signaling paradigm for the cardiovascular system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Elevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin Resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein O-GlcNAc and increased mitochondrial Bcl-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Cardioprotection by N-acetylglucosamine linkage to cellular proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Myocardial reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Increased O-GlcNAc levels during reperfusion lead to improved functional recovery and reduced calpain proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Glucosamine cardioprotection in perfused rat hearts associated with increased O-linked N-acetylglucosamine protein modification and altered p38 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Glutamine-induced protection of isolated rat heart from ischemia/reperfusion injury is mediated via the hexosamine biosynthesis pathway and increased protein O-GlcNAc levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Cell signaling, the essential role of O-GlcNAc!

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

The cytoskeleton and related proteins in the human failing heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: implication of gangliosides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Myocardial protection at a crossroads: the need for translation into clinical therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

At the crossroads of myocardial signaling: the role of Z-discs in intracellular signaling and cardiac function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Elevated expression of O-GlcNAc-modified proteins and O-GlcNAc transferase in corneas of diabetic Goto-Kakizaki rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Cytoskeletal damage during myocardial ischemia: changes in vinculin immunofluorescence staining during total in vitro ischemia in canine heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993218

6 July 2018

Diabetes and the accompanying hyperglycemia impairs cardiomyocyte calcium cycling through increased nuclear O-GlcNAcylation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Evidence of O-linked N-acetylglucosamine in diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Adenovirus-mediated overexpression of O-GlcNAcase improves contractile function in the diabetic heart

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Hexosamine pathway is responsible for inhibition by diabetes of phenylephrine-induced inotropy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

O-GlcNAc expression in developing and ageing mouse brain

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Impact of high glucose/high insulin and dichloroacetate treatment on carbohydrate oxidation and functional recovery after low-flow ischemia and reperfusion in the isolated perfused rat heart

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Heat shock-induced cardioprotection activates cytoskeletal-based cell survival pathways

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Effect of increased expression of cytoskeletal protein vinculin on ischemia-reperfusion injury in ventricular myocytes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00337.2010

21 January 2018

Myocardial cell protection : a challenging time for action and a challenging time for clinical research

1 reference

https://pubmed.ncbi.nlm.nih.gov/20833964

12 December 2020

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A comparison between ranolazine and CVT-4325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20833964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brief, intermediate and prolonged ischemia in the isolated crystalloid perfused rat heart: relationship between susceptibility to arrhythmias and degree of ultrastructural injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/20833964

12 December 2020

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Benchmarking Ventricular Arrhythmias in the Mouse—Revisiting the ‘Lambeth Conventions’ 20 Years On

1 reference

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1 reference

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Identifiers

10.1152/AJPHEART.00337.2010

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833964%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833964%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20833964%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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