(Q28680760)

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

scientific article (publication date: June 2007)

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scholarly article

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes (English)

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genome-wide association study

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type 2 diabetes

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Eleftheria Zeggini

1

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Cecilia Lindgren

3

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Cecilia M Lindgren

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Rachel M Freathy

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author name string

Michael N Weedon

2

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Timothy M Frayling

4

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Katherine S Elliott

5

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Hana Lango

6

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Nicholas J Timpson

7

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John R B Perry

8

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Nigel W Rayner

9

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Jeffrey C Barrett

11

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Beverley Shields

12

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Andrew P Morris

13

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Sian Ellard

14

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Christopher J Groves

15

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Lorna W Harries

16

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Jonathan L Marchini

17

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Katharine R Owen

18

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Beatrice Knight

19

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Lon R Cardon

20

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Mark Walker

21

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Graham A Hitman

22

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Andrew D Morris

23

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Alex S F Doney

24

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Mark I McCarthy

26

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Andrew T Hattersley

27

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language of work or name

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publication date

1 June 2007

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316

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5829

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1336-41

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on focus list of Wikimedia project

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A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

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Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity

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Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas

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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 reference

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

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A haplotype map of the human genome

1 reference

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Aligning multiple genomic sequences with the threaded blockset aligner

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7 April 2017

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

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22 April 2017

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

1 reference

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7 April 2017

A fine-scale map of recombination rates and hotspots across the human genome

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7 April 2017

p16INK4a induces an age-dependent decline in islet regenerative potential

1 reference

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3 June 2018

Cdk5-dependent regulation of glucose-stimulated insulin secretion.

1 reference

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Type 2 diabetes: principles of pathogenesis and therapy

1 reference

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Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex.

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GOLDsurfer: three dimensional display of linkage disequilibrium

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Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

1 reference

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Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

1 reference

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3 June 2018

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