NEK2
gen de la especie Homo sapiens
La serina/treonina quinasa Nek2 es una enzima codificada en humanos por el gen nek2.[1][2]
| Serina/treonina quinasa Nek2 | ||||
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 Estructura tridimensional de la proteína NEK2. | ||||
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| PDB |
Lista de códigos PDB 2jav
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| Identificadores | ||||
| Símbolos | NEK2 (HGNC: 7745) HsPK 21, HsPK21, NEK2A, NLK1 | |||
| Identificadores externos | ||||
| Locus | Cr. 1 q32.3 | |||
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| Entrez |
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| RefSeq (ARNm) |
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Interacciones
editarLa proteína NEK2 ha demostrado ser capaz de interaccionar con:
Referencias
editar- ↑ Schultz SJ, Nigg EA (Feb de 1994). «Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans». Cell Growth Differ 4 (10): 821-30. PMID 8274451.
- ↑ «Entrez Gene: NEK2 NIMA (never in mitosis gene a)-related kinase 2».
- ↑ Lou, Yang; Xie Wei, Zhang Dong-Fang, Yao Jian-hui, Luo Zhao-feng, Wang Yu-Zhen, Shi Yun-Yu, Yao Xue-Biao (Aug. de 2004). «Nek2A specifies the centrosomal localization of Erk2». Biochem. Biophys. Res. Commun. (United States) 321 (2): 495-501. ISSN 0006-291X. PMID 15358203. doi:10.1016/j.bbrc.2004.06.171.
- ↑ Chen, Yumay; Riley Daniel J, Zheng Lei, Chen Phang-Lang, Lee Wen-Hwa (Dec. de 2002). «Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation». J. Biol. Chem. (United States) 277 (51): 49408-16. ISSN 0021-9258. PMID 12386167. doi:10.1074/jbc.M207069200.
- ↑ Chen, Y; Sharp Z D, Lee W H (Sep. de 1997). «HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins». J. Biol. Chem. (UNITED STATES) 272 (38): 24081-7. ISSN 0021-9258. PMID 9295362.
Datos: Q18030036