Dipeptidyl peptidase-4: Difference between revisions

'''Dipeptidyl peptidase-4''' ('''DPP4''' or '''DPPIV'''), also known as '''adenosine deaminase complexing protein 2''' or '''CD26''' ([[cluster of differentiation]] 26) is a [[protein]] that, in humans, is encoded by the ''DPP4'' [[gene]].<ref name="pmid8101391">{{cite journal | vauthors = Kameoka J, Tanaka T, Nojima Y, Schlossman SF, Morimoto C | title = Direct association of adenosine deaminase with a T cell activation antigen, CD26 | journal = Science | volume = 261 | issue = 5120 | pages = 466–9 | date = July 1993 | pmid = 8101391 | doi = 10.1126/science.8101391 | bibcode = 1993Sci...261..466K }}</ref> DPP4 is related to [[FAP (gene)|FAP]], [[DPP8]], and [[DPP9]]. The enzyme was discovered in 1966 by Hopsu-Havu and Glenner,<ref>{{cite journal | vauthors = Hopsu-Havu VK, Glenner GG | title = A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-beta-naphthylamide | journal = Histochemie. Histochemistry. Histochimie | volume = 7 | issue = 3 | pages = 197–201 | date = 1966 | pmid = 5959122 | doi=10.1007/bf00577838| s2cid = 9674831 }}</ref> and as a result of various studies on chemism, was called dipeptidyl peptidase IV [DP IV].