Pentorex

Pentorex
Clinical data
Trade names	Modatrop
Other names	Phenpentermine; α,β-Dimethylamphetamine; β-Methylphentermine
ATC code	none;
Legal status
Legal status	US: Schedule I (positional isomer of Etilamfetamine)[citation needed];
Identifiers
	IUPAC name 2-methyl-3-phenylbutan-2-amine;
CAS Number	434-43-5 ;
PubChem CID	22031;
ChemSpider	20703 ;
UNII	K97CJK0FXR;
CompTox Dashboard (EPA)	DTXSID80861934 ;
ECHA InfoCard	100.006.458
Chemical and physical data
Formula	C11H17N
Molar mass	163.264 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C1=CC=CC=C1)C(C)(C)N;
	InChI InChI=1S/C11H17N/c1-9(11(2,3)12)10-7-5-4-6-8-10/h4-9H,12H2,1-3H3 ; Key:UMWAUEZOGHNSCH-UHFFFAOYSA-N ;
	(what is this?) (verify)

Pentorex, also known as phenpentermine or α,β-dimethylamphetamine and sold under the brand name Modatrop, is a stimulant drug of the amphetamine family related to phentermine (α-methylamphetamine) which is used as an anorectic to assist with weight loss.^[1]^[2] It also acts as a diuretic.^[3] Pentorex was developed by Nordmark in the 1960s.^[4]

It is a derivative of 2-phenyl-3-aminobutane (β-methylamphetamine).

References

^ Behrendt WA, Deininger R (August 1963). "On the Pharmacology of 2-Phenyl-3-Methyl-3-Butylamine, A Substance with Anorexic Action". Arzneimittel-Forschung (in German). 13 (8): 711–6. PMID 14090434.
^ Opitz K, Kemper F, Loeser A (March 1965). "[Comparative study of the anorexigenic potency of some appetite depressants]". Arzneimittel-Forschung (in German). 15 (3): 278–81. PMID 5897218.
^ Opitz K (February 1965). "Natriuretisch-diuretische Wirkung von appetithemmenden Amphetamin-Derivaten". Klinische Wochenschrift (in German). 43 (4): 225–7. doi:10.1007/BF02350860. PMID 14265209. S2CID 46237660.
^ GB patent 995063, "A Substituted Butylamine and Salts thereof", issued 1965-06-10, assigned to Nordmark

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[1] Behrendt WA, Deininger R (August 1963). "On the Pharmacology of 2-Phenyl-3-Methyl-3-Butylamine, A Substance with Anorexic Action". Arzneimittel-Forschung (in German). 13 (8): 711–6. PMID 14090434.

[2] Opitz K, Kemper F, Loeser A (March 1965). "[Comparative study of the anorexigenic potency of some appetite depressants]". Arzneimittel-Forschung (in German). 15 (3): 278–81. PMID 5897218.

[3] Opitz K (February 1965). "Natriuretisch-diuretische Wirkung von appetithemmenden Amphetamin-Derivaten". Klinische Wochenschrift (in German). 43 (4): 225–7. doi:10.1007/BF02350860. PMID 14265209. S2CID 46237660.

[4] GB patent 995063, "A Substituted Butylamine and Salts thereof", issued 1965-06-10, assigned to Nordmark

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