Interior Alaska is in the center of Alaska.

• 64.0708-141.8751 Chicken — a popular rest stop on the Taylor Highway in Alaska
• 65.825556-144.0605562 Circle — an old gold rush settlement on the Yukon River
• 64.037361-145.7321673 Delta Junction — the northwestern terminus of the Alaska Highway, it meets the Richardson Highway
• 64.7875-141.2014 Eagle — many of the buildings from the Gold Rush years are preserved as part of the Eagle Historic District, a National Historic Landmark district
• 64.843611-147.7230565 Fairbanks — home of the University of Alaska
• 64.563917-149.0934726 Nenana — home of the Ice Classic
• 64.751111-147.3519447 North Pole — a summertime attraction for tourists visiting nearby Fairbanks and those traveling to and from the Alaska Highway and Valdez
• 63.336667-142.9855838 Tok — there are a number of state parks in the vicinity of Tok
• 64.741667-156.8759 Galena — a hub for aviation, fishing, and hunting on the banks of the Yukon River; Galena is rich in history and culture, primarily influenced by its Native Alaskan heritage and its significance as a former military base during World War II.

• 63.2-150.31 Denali National Park — dynamic glaciated landscape supports a diversity of wildlife with grizzly bears, caribou, wolves, Dall sheep and moose
• 70.191241-148.4313872 Dalton Highway
• 65-142.83 Yukon - Charley Rivers National Preserve — geology, cultural history, remnants of the last great gold rush, wildlife and scenery. But, best of all, solitude

The greater Fairbanks area is a strange place. Fairbanks proper is like a lot of towns in the lower 48 states. There's a Wal-Mart, a Home Depot and a McDonald's. Don't let this fool you. There are plenty of Alaskan originals.

The rest of the interior is peppered with small, fairly isolated towns and villages. It is advisable to stock up on what you may need in the larger towns as many smaller settlements have very limited retail establishments, and what they do have can be very expensive. Residents in these areas mostly buy their food and other purchases either online or during shopping trips to larger cities. Follow their example, come prepared with food, water, and cooking fuel or firewood for as long as you plan to be in the area plus a day or two just in case. Gasoline is generally available even in the smallest town but it can be very expensive, and so it is advisable to fuel up every time you pass through a larger settlement.

If you are flying to Alaska, you will probably at least land in Anchorage. From there you can get a local flight to many other smaller towns, a rental car, bus tour, or a ticket for the Alaska Railroad. The same options exist if you fly into Fairbanks. If you are coming by road from outside the state you have several options for how to explore the interior, the most popular being the "great circle route". The Glenn, Richardson, and Parks highways comprise a rough circle encompassing hundreds of miles of the Interior and connecting all of its largest settlements as well as Denali National Park. For an unforgettable side trip, consider the Denali Highway, the original road to the park, now lightly traveled and barely maintained. Come well-supplied and ready for extensive potholes and wash boarding. Most rental car companies explicitly forbid travel on this road.

• Fairbanks Airport (FAI ^IATA) has flights from outside Alaska and regional flights.
• Chicken Airport (CKX ^IATA) has regional flights.
• Galena Airport (GAL  ^IATA) is served by Wright Air Service. As of 2022, Everts Air has started service using PC-12 aircraft from Fairbanks. This cuts about an hour of flight time compared to the Cessna Caravans used by Wrights.

Fairbanks is Alaska's second largest city, but only has around 40,000 people. You can easily bike around town if you have a bike with you, and there are lots of bike paths to help with that. It's also a good way to enjoy the scenery around town, since many of the bike paths loop around areas in the outskirts of the city.

Most of the time, though, plan on renting a car if you fly in. It's by far the easiest way to get around and see beyond the city.

The scenery in Alaska's interior speaks for itself. In any weather or season, it is always breathtakingly beautiful.

The Northern Lights are one of the biggest attractions to Alaska. The Interior provides excellent views of them, thanks to a lack of light pollution even around Fairbanks. But do not come in the summertime and expect to see the Aurora. It is the land of the midnight sun for a reason. Summers in Fairbanks mean a complete lack of darkness, which is a really cool experience, but the Lights cannot be seen. If you want a good chance of seeing the Northern Lights but can't handle the cold, September is probably your best bet. The sun is still up for most of the day and it's still quite warm, but it gets quite dark at night and the Lights make their reappearance. Not only that, but the landscape in autumn is awash in all of the bright colors of the season, everyone is outside enjoying the last days of nice weather and since most tourists stick to the summer months, you'll get a friendlier attitude from residents.

Chena Hot Springs, about an hour's drive from Fairbanks, is one of the best attractions in the interior of Alaska. The hotel is run almost entirely on geothermal energy, and the greenhouses grow food for the restaurant. The hot springs themselves are best enjoyed in the wintertime, when the icy air contrasts nicely with the hot water. Because of the lack of light pollution, it's also a wonderful area in which to view the Northern Lights.

In Fairbanks, there is the university. A dynamic research university, there are ongoing studies about everything from the best ways to engineer buildings for the harsh Alaskan landscape to climate change. There's a museum featuring Alaska Native arts, a botanical garden, and a large animal research station with plenty of muskox and reindeer to view. The University of Alaska system as a whole is making a push for sustainability, and this can be easily seen in the many greenhouses dotted around the campus. Many of the vegetables served in the dining halls and cafes are grown right on campus.

Pioneer Park (formerly Alaskaland) is also in Fairbanks. It features pioneer homes that were moved from the downtown area into a central location that people can wander through to learn more about the pioneering history of Alaska.

One of the best things about Fairbanks is that it's home to so many locally owned, mom-and-pop shops that big chain restaurants just don't flourish. For breakfasts, places like the Alaska Coffee Roasting Company and Lulu's Bagels are local favorites. They have great atmospheres in which to sit and chat, and the food is tough to beat.

In the summer, there are many small stands that open up which serve surprisingly good eats. Bun on the Run and Hot Licks Ice Cream are two that locals talk about with reverence and eagerly anticipate when the snow starts to melt.

It will surprise most people to hear that Fairbanks is home to some excellent Thai food. There's a debate among people who live here about which is the best: Lemongrass, Pad Thai, or the Thai House. They each have signature dishes for which people will travel many miles.

SilverGulch brewery is a fairly short drive outside of Fairbanks in Fox. The food and beer are excellent, and the drive is worth it because of the scenery and the views of the Alaska oil pipeline.

If you're camping and would like to stock up on food to cook, the HomeGrown Market has locally raised (and reasonably priced) meats, as well as in-season fruits and vegetables. If you're feeling even reasonably adventurous, try some of the reindeer sausage--it tends toward the spicy and is very tasty. While they're mostly pork, they do have reindeer meat in them. It turns off a lot of tourists, but around the world reindeer is grown for meat and it's yummy, so go ahead and try it.

Alaska is a land of extremes, so be prepared. While Alaska may be known for the cold, summer temperatures in the interior can reach into the 80 °F (27 °C)s and even 90 °F (32 °C)s. Tourists who pack only winter clothes find themselves regretting it.

Also, depending on how hot and dry the summer is, there might be lots of wildfires choking the interior. Check local weather sites before going up there, especially if you have any respiratory conditions. Fairbanks is situated in an arctic desert, so the winter can be equally harsh for those with any respiratory problems. Take that into account when planning your travels.

Because of the harsh conditions, there thankfully is a lack of rabies in Alaska. However, the wildlife is incredibly dangerous and is not to be underestimated. Bears attack, and even more frequently moose will attack people. Even moose that come into the cities and are more habituated to people can suddenly turn and attack someone, so be careful.

One wild animal you will absolutely encounter in large numbers in the summer months is the mosquito. Come prepared.

No matter what season you go up there, bring an attitude of preparedness. What gets people in trouble the most is a rosy idea of what they will encounter. Just be prepared for the unexpected, and for harsher conditions than you may have planned for.