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Protein-coding gene in the species Homo sapiens
Osteoglycin (also called mimecan ), encoded by the OGN gene, is a human protein .[ 5]
This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta . This protein is a small keratan sulfate proteoglycan [ 6] leucine -rich repeats (LRR). The gene expresses three transcript variants.[ 5]
The level of expression of this gene has been correlated with enlarged hearts and more specifically left ventricular hypertrophy .[ 7] [ 8]
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