GPR19

GPR19
Identifiers
Aliases	GPR19, G protein-coupled receptor 19
External IDs	OMIM: 602927; MGI: 892973; HomoloGene: 4476; GeneCards: GPR19; OMA:GPR19 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	12,696,207 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	134,875,541 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; Brodmann area 23; ; endothelial cell; ; middle temporal gyrus; ; primary visual cortex; ; ganglionic eminence; ; cerebellar hemisphere; ; pituitary gland; ; right hemisphere of cerebellum;
	Top expressed in
	spermatocyte; ; medial ganglionic eminence; ; spermatid; ; Rostral migratory stream; ; humerus; ; seminiferous tubule; ; zygote; ; pituitary gland; ; fibula; ; suprachiasmatic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of plasma membrane; membrane; integral component of membrane; plasma membrane; cilium;
Biological process	signal transduction; G protein-coupled receptor signaling pathway; neuropeptide signaling pathway; chemical synaptic transmission; feeding behavior;
	Sources:Amigo / QuickGO
Orthologs
	2842
	14760
	ENSG00000183150
	ENSMUSG00000032641
	Q15760
	Q61121
	NM_006143
NM_001167693; NM_001167694; NM_001167695; NM_001167696; NM_001167697;
	NM_001167699; NM_001167700; NM_008157; NM_001362048; NM_001362049; NM_001362050; NM_001362051; NM_001362052
	NP_006134
NP_001161166; NP_001161167; NP_001161168; NP_001161169; NP_001161171;
	NP_001161172; NP_032183; NP_001348977; NP_001348978; NP_001348979; NP_001348980; NP_001348981
	Wikidata
View/Edit Human	View/Edit Mouse

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Probable G-protein coupled receptor 19 is a protein that in humans is encoded by the GPR19 gene.^[5] GPR19 has been proposed as the receptor for the peptide hormone adropin.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183150 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032641 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GPR19 G protein-coupled receptor 19".
^ Stein LM, Yosten GL, Samson WK (March 2016). "Adropin acts in brain to inhibit water drinking: potential interaction with the orphan G protein-coupled receptor, GPR19". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 310 (6): R476–R480. doi:10.1152/ajpregu.00511.2015. PMC 4867374. PMID 26739651.

O'Dowd BF, Nguyen T, Lynch KR, Kolakowski LF, Thompson M, Cheng R, et al. (October 1996). "A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain". FEBS Letters. 394 (3): 325–329. doi:10.1016/0014-5793(96)00901-5. PMID 8830667. S2CID 1484916.
Montpetit A, Sinnett D (1999). "Physical mapping of the G-protein coupled receptor 19 (GPR19) in the chromosome 12p12.3 region frequently rearranged in cancer cells". Human Genetics. 105 (1–2): 162–164. doi:10.1007/s004390051080. PMID 10480372.
Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Research. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183150 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032641 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GPR19 G protein-coupled receptor 19".

[6] Stein LM, Yosten GL, Samson WK (March 2016). "Adropin acts in brain to inhibit water drinking: potential interaction with the orphan G protein-coupled receptor, GPR19". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 310 (6): R476–R480. doi:10.1152/ajpregu.00511.2015. PMC 4867374. PMID 26739651.

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References

Further reading