Adverse Events of Extracorporeal Ultrasound-Guided High Intensity Focused Ultrasound Therapy

Tinghe Yu and Jun Luo

PLOS ONE, 2011, vol. 6, issue 12, 1-9

Abstract: Background: High-intensity focused ultrasound (HIFU) is considered to be an alternative to surgery. Extracorporeal ultrasound-guided HIFU (USgFU) has been clinically used to treat solid tumors. Preliminary trials in a small sample of a Western population suggested that this modality was safe. Most trials are performed in China thereby providing comprehensive data for understanding the safety profile. The aim of this study was to evaluate adverse events of USgFU therapy. Methods and Findings: Clinical data were searched in 2 Chinese databases. Adverse events of USgFU were summarized and compared with those of magnetic resonance-guided HIFU (MRgFU; for uterine, bone or breast tumor) and transrectal ultrasound-guided HIFU (for prostate cancer or benign prostate hyperplasia). USgFU treatment was performed using 7 types of device. Side effects were evaluated in 13262 cases. There were fewer adverse events in benign lesions than in malignant lesions (11.81% vs. 21.65%, p

Date: 2011
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0026110

DOI: 10.1371/journal.pone.0026110

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