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The Santa Ysabel Stakes is an American Thoroughbred horse race once run during January but now run in March at Santa Anita Park in Arcadia, California. The race is open to fillies, age three, willing to race one and one-sixteenths miles (8.5 furlongs) on the dirt. The race is a Grade III event with a current purse of $100,000 and is part of the Road to the Kentucky Oaks. Inaugurated in 1968, the Santa Ysabel Stakes was contested at 7 furlongs in 1970 but has otherwise been run at 1+1⁄16 miles. It was run in two divisions in 1968, 1970, 1972, and 1979.