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PCBS: Principal Component BiSulfite

A system for fast, accurate, and flexible whole genome bisulfite sequencing (WGBS) data analysis of two-condition comparisons. Principal Component BiSulfite, 'PCBS', assigns methylated loci eigenvector values from the treatment-delineating principal component in lieu of running millions of pairwise statistical tests, which dramatically increases analysis flexibility and reduces computational requirements. Methods: <https://katlande.github.io/PCBS/articles/Differential_Methylation.html>.

Version: 0.1.1
Depends: R (≥ 2.10)
Imports: ggplot2, tibble, ggrepel, dplyr, data.table
Published: 2024-08-27
DOI: 10.32614/CRAN.package.PCBS
Author: Kathryn Lande [aut, cre, cph]
Maintainer: Kathryn Lande <kathryn.lande at mail.mcgill.ca>
BugReports: https://github.com/katlande/PCBS/issues
License: GPL-3
URL: https://github.com/katlande/PCBS
NeedsCompilation: no
CRAN checks: PCBS results

Documentation:

Reference manual: PCBS.pdf

Downloads:

Package source: PCBS_0.1.1.tar.gz
Windows binaries: r-devel: PCBS_0.1.1.zip, r-release: PCBS_0.1.1.zip, r-oldrel: PCBS_0.1.1.zip
macOS binaries: r-release (arm64): PCBS_0.1.1.tgz, r-oldrel (arm64): PCBS_0.1.1.tgz, r-release (x86_64): PCBS_0.1.1.tgz, r-oldrel (x86_64): PCBS_0.1.1.tgz
Old sources: PCBS archive

Linking:

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