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Član 6 porodice rastvornih nosača 17 (vezikulski glutamat-transporter) je protein koji je kod ljudi kodiran genom SLC17A6. [5]

SLC17A6
Identifikatori
AliasiSLC17A6
Vanjski ID-jeviOMIM: 607563 MGI: 2156052 HomoloGene: 121617 GeneCards: SLC17A6
Lokacija gena (čovjek)
Hromosom 11 (čovjek)
Hrom.Hromosom 11 (čovjek)[1]
Hromosom 11 (čovjek)
Genomska lokacija za SLC17A6
Genomska lokacija za SLC17A6
Bend11p14.3Početak22,338,381 bp[1]
Kraj22,379,503 bp[1]
Lokacija gena (miš)
Hromosom 7 (miš)
Hrom.Hromosom 7 (miš)[2]
Hromosom 7 (miš)
Genomska lokacija za SLC17A6
Genomska lokacija za SLC17A6
Bend7|7 B4Početak51,271,754 bp[2]
Kraj51,320,867 bp[2]
Ontologija gena
Molekularna funkcija symporter activity
L-glutamate transmembrane transporter activity
neurotransmitter transmembrane transporter activity
Ćelijska komponenta integral component of membrane
neuron projection
međućelijske veze
sinapsa
synaptic vesicle membrane
membrana
GO:0016023 citoplazmatska vezikula
integral component of synaptic vesicle membrane
excitatory synapse
Biološki proces neurotransmitter transport
ion transport
sodium ion transport
GO:0015915 transport
transmembrane transport
L-glutamate transmembrane transport
synaptic transmission, glutamatergic
regulation of synapse structure or activity
neurotransmitter loading into synaptic vesicle
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_020346

NM_080853
NM_001355150

RefSeq (bjelančevina)

NP_065079

NP_543129
NP_001342079

Lokacija (UCSC)Chr 11: 22.34 – 22.38 MbChr 7: 51.27 – 51.32 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš
Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 582 aminokiseline, а molekulska težina 64.392 Da.[6]

1020304050
MESVKQRILAPGKEGLKNFAGKSLGQIYRVLEKKQDTGETIELTEDGKPL
EVPERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVN
NSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLA
ANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHG
IWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYG
SFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFK
TPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGM
LSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLL
LVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISN
GVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASG
EKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATTQA
NGGWPSGWEKKEEFVQGEVQDSHSYKDRVDYS

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000091664 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030500 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Solute carrier family 17 (vesicular glutamate transporter), member 6". Pristupljeno 2. 2. 2016.
  6. ^ "UniProt, Q9P2U8". Pristupljeno 27. 8. 2021.