Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis (Q90365735)

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scientific article published on 07 December 2018

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English	Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis	scientific article published on 07 December 2018

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Europe PubMed Central

PMC publication ID

6385749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

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13 April 2020

title

Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis (English)

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Europe PubMed Central

PMC publication ID

6385749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

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13 April 2020

main subject

adipogenesis

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author

Mi-Jeong Lee

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1

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Europe PubMed Central

PMC publication ID

6385749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

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13 April 2020

author name string

R Taylor Pickering

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2

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6385749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

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13 April 2020

Varuna Shibad

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3

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6385749

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13 April 2020

Yuanyuan Wu

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4

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6385749

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13 April 2020

Kalypso Karastergiou

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5

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PMC publication ID

6385749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

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13 April 2020

Mike Jager

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6

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6385749

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13 April 2020

Matthew D Layne

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7

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6385749

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13 April 2020

Susan K Fried

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8

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6385749

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13 April 2020

publication date

7 December 2018

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6385749

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13 April 2020

published in

Diabetes

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PMC publication ID

6385749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

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13 April 2020

volume

68

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6385749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

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13 April 2020

issue

3

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Europe PubMed Central

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6385749

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

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13 April 2020

page(s)

587-597

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6385749

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13 April 2020

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ImageJ

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11 June 2022

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cites work

Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Transforming growth factor beta (TGF-beta) inhibits the differentiation of human adipocyte precursor cells in primary culture

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Lipoprotein lipase regulation by insulin and glucocorticoid in subcutaneous and omental adipose tissues of obese women and men.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid1

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Roles of autocrine TGF-beta receptor and Smad signaling in adipocyte differentiation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Comparison of proliferation and differentiation capacity of human adipocyte precursor cells from the omental and subcutaneous adipose tissue depot of obese subjects

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Modulation of glucocorticoid receptor function via phosphorylation.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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inferred from PubMed ID database lookup

Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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inferred from PubMed ID database lookup

Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Transcription factor Smad3 is required for the inhibition of adipogenesis by retinoic acid

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Expression of genes related to glucocorticoid action in human subcutaneous and omental adipose tissue

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Activin a plays a critical role in proliferation and differentiation of human adipose progenitors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Pathways regulated by glucocorticoids in omental and subcutaneous human adipose tissues: a microarray study

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGFbeta family members are key mediators in the induction of myofibroblast phenotype of human adipose tissue progenitor cells by macrophages

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Intrinsic differences in adipocyte precursor cells from different white fat depots.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

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Human but not mouse adipogenesis is critically dependent on LMO3

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Prolonged efficiency of siRNA-mediated gene silencing in primary cultures of human preadipocytes and adipocytes.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-β signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glucocorticoid receptor, not the mineralocorticoid receptor, plays the dominant role in adipogenesis and adipokine production in human adipocytes

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Optimal protocol for the differentiation and metabolic analysis of human adipose stromal cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectodomain shedding of TβRIII is required for TβRIII-mediated suppression of TGF-β signaling and breast cancer migration and invasion

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and the depot-specific secretome of human preadipocytes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Omental adipose tissue fibrosis and insulin resistance in severe obesity.

1 reference

stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

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Fibrosis-streaks and splatters: Some things are not always what they seem to be.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 induces impairment in human subcutaneous adipogenesis in obesity-associated insulin resistance

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relevance of omental pericellular adipose tissue collagen in the pathophysiology of human abdominal obesity and related cardiometabolic risk

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-fat diet-induced obesity regulates MMP3 to modulate depot- and sex-dependent adipose expansion in C57BL/6J mice

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depot Dependent Effects of Dexamethasone on Gene Expression in Human Omental and Abdominal Subcutaneous Adipose Tissues from Obese Women

1 reference

stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose tissue macrophages impair preadipocyte differentiation in humans

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A PDGFRα-Mediated Switch toward CD9high Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoids Regulate Adipogenesis Involving the TGFβ/SMAD and Wnt/β-Catenin Pathways in Human Bone Marrow Mesenchymal Stem Cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Adipose Mesenchymal Cells Inhibit Melanocyte Differentiation and the Pigmentation of Human Skin via Increased Expression of TGF-β1.

1 reference

stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/30530781

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dually modified transmembrane proteoglycans in development and disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30530781

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.2337/DB18-0955

1 reference

stated in

Europe PubMed Central

PMC publication ID

6385749

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 April 2020

PMC publication ID

6385749

1 reference

stated in

Europe PubMed Central

PMC publication ID

6385749

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 April 2020

PubMed publication ID

30530781

1 reference

stated in

Europe PubMed Central

PMC publication ID

6385749

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

retrieved

13 April 2020

 

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