Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models (Q90310402)

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scientific article published on 14 March 2020

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English	Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models	scientific article published on 14 March 2020

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scholarly article

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12 April 2020

Autophagy-mediated occludin degradation contributes to blood-brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models (English)

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12 April 2020

blood–brain barrier

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based on heuristic

inferred from title

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based on heuristic

inferred from title

10

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12 April 2020

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Kyeong-A Kim

1

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12 April 2020

Donghyun Kim

2

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12 April 2020

Jeong-Hyeon Kim

3

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12 April 2020

Young-Jun Shin

4

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12 April 2020

Eun-Sun Kim

5

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12 April 2020

Muhammad Akram

6

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12 April 2020

Eun-Hye Kim

7

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12 April 2020

Arshad Majid

8

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12 April 2020

Seung-Hoon Baek

9

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12 April 2020

publication date

14 March 2020

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12 April 2020

Fluids and Barriers of the CNS

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Europe PubMed Central

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12 April 2020

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12 April 2020

1

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12 April 2020

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12 April 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7071658/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

COOH Terminus of Occludin Is Required for Tight Junction Barrier Function in Early Xenopus Embryos

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https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton

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https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells

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https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

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Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins

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https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Occludin: structure, function and regulation

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https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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The blood-brain barrier/neurovascular unit in health and disease

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https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral ischemia enhances tyrosine phosphorylation of occludin in brain capillaries

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Tight junctions contain oligomeric protein assembly critical for maintaining blood-brain barrier integrity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood-brain barrier tight junction permeability and ischemic stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Structure and function of the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Participation of the second extracellular loop of claudin-5 in paracellular tightening against ions, small and large molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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A practical guide to evaluating colocalization in biological microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Autophagosomes accumulation is associated with β‐amyloid deposits and secondary damage in the thalamus after focal cortical infarction in hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of the neurovascular unit: disease cause or consequence?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy--the friendly fire in endothelial cell regeneration. Focus on "Autophagy in endothelial progenitor cells is cytoprotective in hypoxic conditions".

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases and blood-brain barrier disruption in acute ischemic stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy: a critical regulator of cellular metabolism and homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An overview of autophagy: morphology, mechanism, and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The involvement of autophagy pathway in exaggerated ischemic brain damage in diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development, maintenance and disruption of the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of Integrity: Impairment of the Blood-brain Barrier in Heavy Metal-associated Ischemic Stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the protective potential of brain microvascular endothelial cell autophagy on blood-brain barrier integrity during experimental cerebral ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autosis and autophagic cell death: the dark side of autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy protects human brain microvascular endothelial cells against methylglyoxal-induced injuries, reproducible in a cerebral ischemic model in diabetic rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric Oxide Interacts with Caveolin-1 to Facilitate Autophagy-Lysosome-Mediated Claudin-5 Degradation in Oxygen-Glucose Deprivation-Treated Endothelial Cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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MicroRNA-9 Mediates the Cell Apoptosis by Targeting Bcl2l11 in Ischemic Stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCT complex restricts neuropathogenic protein aggregation via autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of the Blood-Brain Barrier as a Therapeutic Strategy for Brain Damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasomal and Autophagic Degradation Systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADPH Oxidase-Related Pathophysiology in Experimental Models of Stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Autophagy in Endothelial Damage and Blood-Brain Barrier Disruption in Ischemic Stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy promotes angiogenesis via AMPK/Akt/mTOR signaling during the recovery of heat-denatured endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative Toxicity Study of Docetaxel and Nanoxel, a Docetaxel-Loaded Micellar Formulation Using Cultured and Blood Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32169114

12 December 2020

based on heuristic

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Identifiers

10.1186/S12987-020-00182-8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32169114%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32169114%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32169114%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

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