Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model (Q83940718)

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scientific article published on 07 June 2006

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English	Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model	scientific article published on 07 June 2006

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Europe PubMed Central

PubMed publication ID

16758333

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29 January 2020

title

Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model (English)

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Europe PubMed Central

PubMed publication ID

16758333

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29 January 2020

main subject

pharmacokinetics

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author

Ronald N. Hines

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4

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Europe PubMed Central

PubMed publication ID

16758333

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29 January 2020

author name string

Feng Yang

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1

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Europe PubMed Central

PubMed publication ID

16758333

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29 January 2020

Xianping Tong

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2

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PubMed publication ID

16758333

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29 January 2020

D Gail McCarver

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3

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PubMed publication ID

16758333

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29 January 2020

Daniel A Beard

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5

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PubMed publication ID

16758333

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16758333%20AND%20SRC:MED&resulttype=core&format=json

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29 January 2020

publication date

7 June 2006

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Europe PubMed Central

PubMed publication ID

16758333

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16758333%20AND%20SRC:MED&resulttype=core&format=json

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29 January 2020

published in

Journal of Pharmacokinetics and Pharmacodynamics

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Europe PubMed Central

PubMed publication ID

16758333

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29 January 2020

volume

33

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16758333

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29 January 2020

issue

4

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Europe PubMed Central

PubMed publication ID

16758333

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29 January 2020

page(s)

485-518

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PubMed publication ID

16758333

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29 January 2020

cites work

Disposition of methadone in methadone maintenance

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

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Interaction of methadone with substrates of human hepatic cytochrome P450 3A4.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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A statistical analysis of the internal organ weights of normal Japanese people

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methadone--metabolism, pharmacokinetics and interactions

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

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The use of plasma levels to optimize methadone maintenance treatment

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

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Drug interactions with patient-controlled analgesia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolic fate of the optical isomers of methadone

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-state pharmacokinetics of methadone in opioid addicts

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation and growth of renal function: dosing renally cleared drugs in children

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver volume in children measured by computed tomography

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Nomograms for the prediction of patient's plasma volume in plasma exchange therapy from height, weight, and hematocrit

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of methadone and its primary metabolite in 20 opiate addicts

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gross tissue weights in the human body by cadaver dissection

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Enteral methadone to expedite fentanyl discontinuation and prevent opioid abstinence syndrome in the PICU.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

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Influence of plasma-protein binding on analgesic effect of methadone in rats with spontaneous withdrawal

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

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Alpha 1-acid glycoprotein levels in human immunodeficiency virus-infected subjects on antiretroviral regimens

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of age-related changes in body weight and organ weights from birth to adolescence in humans.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Methadone use in cancer patients with pain: a review

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation and prediction of blood volume in infants and children

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling interindividual variation in physiological factors used in PBPK models of humans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Methadone: a review of its pharmacokinetic/pharmacodynamic properties.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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The gastrointestinal absorption of methadone in the rat

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Protein binding predictions in infants

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Perspectives in pharmacokinetics. Physiologically based pharmacokinetic modeling as a tool for drug development

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of methadone in man.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of methadone

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Standard splenic volume in children and young adults measured from CT images

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Tolerance, withdrawal, and physical dependency after long-term sedation and analgesia of children in the pediatric intensive care unit

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of methadone in man after a single oral dose

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of uncertainty in input parameters to pharmacokinetic models and the resulting uncertainty in output

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms

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PubMed

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12 December 2020

based on heuristic

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective pharmacokinetics of methadone in chronic pain patients

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methadone maintenance: a review and critique

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental expression of the major human hepatic CYP3A enzymes

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

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Physiologically based pharmacokinetics in drug development and regulatory science: a workshop report (Georgetown University, Washington, DC, May 29-30, 2002).

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A review of patients on methadone maintenance.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of relative weight and Body Mass Index for the determination of adiposity

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologically based pharmacokinetic (PBPK) modeling of caffeine and theophylline in neonates and adults: implications for assessing children's risks from environmental agents

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in brain weights during the span of human life: relation of brain weights to body heights and body weights

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

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Human physiologically based pharmacokinetic model for propofol

1 reference

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of methadone disposition in the pregnant rat by means of a physiological flow model

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenomics as an aspect of molecular autopsy for forensic pathology/toxicology: does genotyping CYP 2D6 serve as an adjunct for certifying methadone toxicity?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic anatomical and physiological data for use in radiological protection: reference values. A report of age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

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inferred from PubMed ID database lookup

The influence of age, sex, race, and body habitus on kidney weight in humans

1 reference

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retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimating the surface area of the human body.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methadone as treatment for iatrogenic narcotic dependency in pediatric intensive care unit patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methadone plasma protein binding: alterations in cancer and displacement from alpha 1-acid glycoprotein

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16758333

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of methadone enantiomers after a single oral dose of racemate

1 reference

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https://pubmed.ncbi.nlm.nih.gov/16758333

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12 December 2020

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Identifiers

DOI

10.1007/S10928-006-9018-0

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16758333

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16758333%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Dimensions Publication ID

1006344107

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PubMed publication ID

16758333

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16758333

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16758333%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

 

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