Phase II study of sphingosomal vincristine in patients with recurrent or refractory adult acute lymphocytic leukemia (Q81581465)

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10 January 2020

title

Phase II study of sphingosomal vincristine in patients with recurrent or refractory adult acute lymphocytic leukemia (English)

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acute lymphocytic leukemia

10 January 2020

main subject

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adult acute lymphocytic leukemia

inferred from title

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10 January 2020

Guillermo Garcia-Manero

object named as

Guillermo Garcia-Manero

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10 January 2020

Deborah A Thomas

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10 January 2020

Andreas H Sarris

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10 January 2020

Jorge Cortes

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10 January 2020

Stefan Faderl

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10 January 2020

Susan O'Brien

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10 January 2020

Francis J Giles

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10 January 2020

Maria A Rodriguez

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10 January 2020

Hagop Kantarjian

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10 January 2020

publication date

1 January 2006

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10 January 2020

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10 January 2020

volume

106

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issue

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page(s)

120-127

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The binding of vincristine, vinblastine and colchicine to tubulin

10 January 2020

cites work

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7 January 2021

Apoptosis as a mechanism of cell death induced by different chemotherapeutic drugs in human leukemic T-lymphocytes

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7 January 2021

Cell death induced by vincristine in the intestinal crypts of mice and in a human Burkitt's lymphoma cell line

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7 January 2021

Vincristine saturation of cellular binding sites and its cytotoxic activity in human lymphoblastic leukemia cells: mechanism of inoculum effect

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7 January 2021

Full dose vincristine (without 2-mg dose limit) in the treatment of lymphomas

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7 January 2021

Remission induction therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of vincristine, corticosteroids, L-asparaginase and anthracyclines

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7 January 2021

Vincristine pharmacokinetics after repetitive dosing in children.

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7 January 2021

Pharmacokinetics of vincristine in children and adolescents with acute lymphocytic leukemia

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7 January 2021

Polyethylene glycol-liposomal doxorubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the management of AIDS-related Kaposi's sarcoma

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7 January 2021

Liposomal encapsulated anthracyclines: new therapeutic horizons

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7 January 2021

Liposome encapsulated vincristine: preclinical toxicologic and pharmacologic comparison with free vincristine and empty liposomes in mice, rats and dogs

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7 January 2021

Liposomal vincristine for the treatment of human acute lymphoblastic leukaemia in severe combined immunodeficient (SCID) mice

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7 January 2021

Pharmacokinetics and antitumor activity of vincristine entrapped in vesicular phospholipid gels

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7 January 2021

In vivo administration of liposomal vincristine sensitizes drug-resistant human solid tumors

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7 January 2021

Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia

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7 January 2021

Pharmacology of liposomal vincristine in mice bearing L1210 ascitic and B16/BL6 solid tumours

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7 January 2021

Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models

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7 January 2021

Preclinical pharmacology, toxicology and efficacy of sphingomyelin/cholesterol liposomal vincristine for therapeutic treatment of cancer

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7 January 2021

Vincristine-induced dermal toxicity is significantly reduced when the drug is given in liposomes

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7 January 2021

Phase I study of liposomal vincristine

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7 January 2021

Liposomal vincristine in relapsed non-Hodgkin's lymphomas: early results of an ongoing phase II trial.

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7 January 2021

Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-alpha therapy. The Leukemia Service

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7 January 2021

Nonparametric Estimation from Incomplete Observations

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7 January 2021

Primary refractory and relapsed adult acute lymphoblastic leukemia: characteristics, treatment results, and prognosis with salvage therapy

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7 January 2021

Salvage therapy for refractory or relapsed acute lymphocytic leukemia

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7 January 2021

New agents in the treatment of acute lymphocytic leukaemia

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7 January 2021

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

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7 January 2021

Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate

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7 January 2021

Combination therapy with methotrexate, vincristine, polyethylene-glycol conjugated-asparaginase, and prednisone in the treatment of patients with refractory or recurrent acute lymphoblastic leukemia

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7 January 2021

Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia

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7 January 2021

Pharmacokinetics of nelarabine and 9-beta-D-arabinofuranosyl guanine in pediatric and adult patients during a phase I study of nelarabine for the treatment of refractory hematologic malignancies

1 reference

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7 January 2021

Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia

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7 January 2021

Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia

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7 January 2021

Identifiers

DOI

10.1002/CNCR.21595

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16331634%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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