A synthetic HIV-1 Tat protein breaches the skin barrier and elicits Tat-neutralizing antibodies and cellular immunity (Q81021581)

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5 January 2020

title

A synthetic HIV-1 Tat protein breaches the skin barrier and elicits Tat-neutralizing antibodies and cellular immunity (English)

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5 January 2020

author name string

Charalambos D Partidos

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5 January 2020

Emmanuel Moreau

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5 January 2020

Olivier Chaloin

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5 January 2020

Mélanie Tunis

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5 January 2020

Jean-Paul Briand

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5 January 2020

Claude Desgranges

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5 January 2020

Sylviane Muller

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5 January 2020

publication date

1 December 2004

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European Journal of Immunology

5 January 2020

published in

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5 January 2020

volume

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5 January 2020

issue

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5 January 2020

page(s)

3723-3731

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Targeting Tat and IFN(alpha) as a therapeutic AIDS vaccine

5 January 2020

cites work

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7 January 2021

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7 January 2021

HIV-1 Tat protein mimicry of chemokines

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Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro

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Tat-mediated delivery of heterologous proteins into cells

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7 January 2021

Cellular uptake of the tat protein from human immunodeficiency virus

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7 January 2021

Sequence conservation and antibody cross-recognition of clade B human immunodeficiency virus (HIV) type 1 Tat protein in HIV-1-infected Italians, Ugandans, and South Africans

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7 January 2021

Skin immunization made possible by cholera toxin

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7 January 2021

Transcutaneous immunization and immunostimulant strategies: capitalizing on the immunocompetence of the skin

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7 January 2021

Delivering vaccines into the skin without needles and syringes

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7 January 2021

Transcutaneous immunization with bacterial ADP-ribosylating exotoxins, subunits, and unrelated adjuvants

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7 January 2021

Immunization onto bare skin with heat-labile enterotoxin of Escherichia coli enhances immune responses to coadministered protein and peptide antigens and protects mice against lethal toxin challenge

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7 January 2021

The LTR72 mutant of heat-labile enterotoxin of Escherichia coli enhances the ability of peptide antigens to elicit CD4(+) T cells and secrete gamma interferon after coapplication onto bare skin

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7 January 2021

Transcutaneous immunization with tetanus toxoid and mutants of Escherichia coli heat-labile enterotoxin as adjuvants elicits strong protective antibody responses.

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7 January 2021

Immunity under the skin: potential application for topical delivery of vaccines.

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7 January 2021

Transcutaneous immunization: a human vaccine delivery strategy using a patch

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7 January 2021

Safety and immunogenicity of a prototype enterotoxigenic Escherichia coli vaccine administered transcutaneously

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7 January 2021

A quantitative bioassay for HIV-1 based on trans-activation.

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7 January 2021

Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans

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7 January 2021

Identification and characterization of a cell surface proteoglycan on keratinocytes

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7 January 2021

Mucosal delivery of the human immunodeficiency virus-1 Tat protein in mice elicits systemic neutralizing antibodies, cytotoxic T lymphocytes and mucosal IgA.

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7 January 2021

Efficient mucosal delivery of the HIV-1 Tat protein using the synthetic lipopeptide MALP-2 as adjuvant.

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7 January 2021

Characterization of murine monoclonal antibodies to the tat protein from human immunodeficiency virus type 1

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7 January 2021

Tat-neutralizing antibodies in vaccinated macaques

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7 January 2021

Generation and characterization of neutralizing human monoclonal antibodies against human immunodeficiency virus type 1 Tat antigen

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7 January 2021

Two B cell epitopes of HIV-1 Tat protein have limited antigenic polymorphism in geographically diverse HIV-1 strains

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7 January 2021

Innate and adaptive mucosal immunity in protection against HIV infection.

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7 January 2021

Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells

1 reference

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7 January 2021

The induction of systemic and mucosal immune responses to antigen-adjuvant compositions administered into the skin: alterations in the migratory properties of dendritic cells appears to be important for stimulating mucosal immunity

1 reference

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7 January 2021

Transcutaneous immunization induces mucosal and systemic immunity: a potent method for targeting immunity to the female reproductive tract

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7 January 2021

Epicutaneous application of CpG oligodeoxynucleotides with peptide or protein antigen promotes the generation of CTL.

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7 January 2021

Modulation of immune responses with transcutaneously deliverable adjuvants

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7 January 2021

Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses

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7 January 2021

Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor beta1 and beta2 chain expression

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1002/EJI.200425313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15549730%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15549730%20AND%20SRC:MED&resulttype=core&format=json