The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells (Q80146459)

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scientific article published on 02 December 2007

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English	The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells	scientific article published on 02 December 2007

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29 December 2019

The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells (English)

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29 December 2019

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Kenya Honda

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29 December 2019

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Shin-ichi Kano

1

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29 December 2019

Kojiro Sato

2

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29 December 2019

Yasuyuki Morishita

3

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29 December 2019

Sabine Vollstedt

4

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29 December 2019

Sunhwa Kim

5

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29 December 2019

Keith Bishop

6

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29 December 2019

Masato Kubo

8

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29 December 2019

Tadatsugu Taniguchi

9

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29 December 2019

publication date

2 December 2007

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29 December 2019

Nature Immunology

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29 December 2019

9

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29 December 2019

1

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29 December 2019

34-41

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29 December 2019

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Signaling and transcription in T helper development

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-17 family cytokines and the expanding diversity of effector T cell lineages

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

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7 January 2021

based on heuristic

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms regulating Th1 immune responses

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

IRF family of transcription factors as regulators of host defense

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Multistage regulation of Th1-type immune responses by the transcription factor IRF-1

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of IFN regulatory factor-1 binding site in IL-12 p40 gene promoter

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

IFN-gamma represses IL-4 expression via IRF-1 and IRF-2

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Positive and negative regulation of IL-12 receptor expression of naive CD4(+) T cells by CD28/CD152 co-stimulation

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Transforming growth factor-beta induces development of the T(H)17 lineage

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

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Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

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Interleukin-15 induces IL-12 receptor beta1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

T helper type 1-specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-gamma promoter are Stat4 dependent

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease

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Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease

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Detection of interferon regulatory factor-1 in lamina propria mononuclear cells in Crohn's disease

1 reference

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7 January 2021

based on heuristic

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

inferred from DOI database lookup

Immune response in mice that lack the interferon-gamma receptor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1538

7 January 2021

based on heuristic

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Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1 reference

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7 January 2021

based on heuristic

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Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

1 reference

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7 January 2021

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Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming

1 reference

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7 January 2021

based on heuristic

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18059273%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18059273%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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