Amino acid activation and polymerization at modular multienzymes in nonribosomal peptide biosynthesis (Q86624555)

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29 February 2020

title

Amino acid activation and polymerization at modular multienzymes in nonribosomal peptide biosynthesis (English)

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29 February 2020

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29 February 2020

T Stein

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29 February 2020

publication date

1 September 1996

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29 February 2020

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29 February 2020

volume

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issue

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29 February 2020

page(s)

201-227

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Molecular characterization of the enniatin synthetase gene encoding a multifunctional enzyme catalysing N-methyldepsipeptide formation in Fusarium scirpi

29 February 2020

cites work

1 reference

12 December 2020

Crystal structure of a deletion mutant of a tyrosyl-tRNA synthetase complexed with tyrosine

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12 December 2020

Effect of single base substitutions at glycine-870 codon of gramicidin S synthetase 2 gene on proline activation.

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12 December 2020

Organic compound synthesis on the primitive earth

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12 December 2020

Characterization of the surfactin synthetase multi-enzyme complex

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12 December 2020

Modular structure of peptide synthetases revealed by dissection of the multifunctional enzyme GrsA.

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12 December 2020

Molecular cloning and sequencing of a cDNA encoding the acyl carrier protein and its flanking domains in the mammalian fatty acid synthetase

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12 December 2020

Complexes of sequential metabolic enzymes

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12 December 2020

Identification of the ATP binding site in tyrocidine synthetase 1 by selective modification with fluorescein 5'-isothiocyanate.

1 reference

12 December 2020

The cluster of penicillin biosynthetic genes. Identification and characterization of the pcbAB gene encoding the alpha-aminoadipyl-cysteinyl-valine synthetase and linkage to the pcbC and penDE genes

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12 December 2020

Structural and functional relationships between aminoacyl-tRNA synthetases

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12 December 2020

Identification and characterization of phosphinothricin-tripeptide biosynthetic genes in Streptomyces viridochromogenes

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12 December 2020

Molecular cloning and nucleotide sequence of the gramicidin S synthetase 1 gene

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12 December 2020

The protein thiotemplate mechanism of synthesis for the peptide antibiotics produced by Bacillus brevis.

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12 December 2020

Rational Design of Peptide Antibiotics by Targeted Replacement of Bacterial and Fungal Domains

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12 December 2020

The functions and consensus motifs of nine types of peptide segments that form different types of nucleotide-binding sites

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12 December 2020

Modification of the amino acid specificity of tyrosyl-tRNA synthetase by protein engineering

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12 December 2020

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12 December 2020

Reaction mechanism of gramicidin S synthetase 1, phenylalanine racemase, of Bacillus brevis

1 reference

12 December 2020

The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum

1 reference

12 December 2020

δ-L -(α-Aminoadipoyl)-L -cysteinyl-D -valine synthetase: the order of peptide bond formation and timing of the epimerisation reaction

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12 December 2020

Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA

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12 December 2020

Aminoacyl tRNA synthetases: general scheme of structure-function relationships in the polypeptides and recognition of transfer RNAs

1 reference

12 December 2020

The isopenicillin-N acyltransferase of Penicillium chrysogenum has isopenicillin-N amidohydrolase, 6-aminopenicillanic acid acyltransferase and penicillin amidase activities, all of which are encoded by the single penDE gene

1 reference

12 December 2020

Purification and characterization of eucaryotic alanine racemase acting as key enzyme in cyclosporin biosynthesis.

1 reference

12 December 2020

ATP binding in peptide synthetases: determination of contact sites of the adenine moiety by photoaffinity labeling of tyrocidine synthetase 1 with 2-azidoadenosine triphosphate.

1 reference

12 December 2020

Biosynthesis of small peptides

1 reference

12 December 2020

Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate

1 reference

12 December 2020

The primary structure of spinach acyl carrier protein

1 reference

12 December 2020

The Rhizobium leguminosarum nodulation gene nodF encodes a polypeptide similar to acyl-carrier protein and is regulated by nodD plus a factor in pea root exudate.

1 reference

12 December 2020

Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues

1 reference

12 December 2020

The predicted secondary structures of the nucleotide-binding sites of six cation-transporting ATPases lead to a probable tertiary fold

1 reference

12 December 2020

Nonribosomal biosynthesis of peptide antibiotics

1 reference

12 December 2020

Prebiotic syntheses of vitamin coenzymes: I. Cysteamine and 2-mercaptoethanesulfonic acid (coenzyme M).

1 reference

12 December 2020

The proline-activating activity of the multienzyme gramicidin S synthetase 2 can be recovered on a 115-kDa tryptic fragment

1 reference

12 December 2020

Two enzymes involved in biosynthesis of the host-selective phytotoxin HC-toxin

1 reference

12 December 2020

Prebiotic syntheses of vitamin coenzymes: II. Pantoic acid, pantothenic acid, and the composition of coenzyme A.

1 reference

12 December 2020

Plastid-localised seed acyl-carrier protein of Brassica napus is encoded by a distinct, nuclear multigene family

1 reference

12 December 2020

A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids

1 reference

12 December 2020

The cyclic peptide synthetase catalyzing HC-toxin production in the filamentous fungus Cochliobolus carbonum is encoded by a 15.7-kilobase open reading frame

1 reference

12 December 2020

Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.

1 reference

12 December 2020

Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs

1 reference

12 December 2020

Gramicidin S synthetase 1 (phenylalanine racemase), a prototype of amino acid racemases containing the cofactor 4'-phosphopantetheine.

1 reference

12 December 2020

Glutathione metabolism and its selective modification

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12 December 2020

Structural relationships and the classification of aminoacyl-tRNA synthetases

1 reference

12 December 2020

Analysis of a mutant amino acid-activating domain of surfactin synthetase bearing a serine-to-alanine substitution at the site of carboxylthioester formation.

1 reference

12 December 2020

Structural model for the reaction mechanism of glutamine synthetase, based on five crystal structures of enzyme-substrate complexes

1 reference

12 December 2020

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12 December 2020

Beta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.

1 reference

12 December 2020

Characterization of tyrocidine synthetase 1 (TY1): requirement of posttranslational modification for peptide biosynthesis

1 reference

12 December 2020

Dissection of functional domains of the yeast proton-pumping ATPase by directed mutagenesis.

1 reference

12 December 2020

Nucleotide sequence of Rhizobium meliloti RCR2011 genes involved in host specificity of nodulation

1 reference

12 December 2020

Chemical and biological evolution of nucleotide-binding protein

1 reference

12 December 2020

Selection by differential molecular survival: a possible mechanism of early chemical evolution

1 reference

12 December 2020

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

12 December 2020

A common fold for peptide synthetases cleaving ATP to ADP: glutathione synthetase and D-alanine:d-alanine ligase of Escherichia coli

1 reference

12 December 2020

Cyclosporin synthetase. The most complex peptide synthesizing multienzyme polypeptide so far described

1 reference

12 December 2020

Structural comparison, modes of expression, and putative cis-acting elements of the two 4-coumarate: CoA ligase genes in potato

1 reference

12 December 2020

An active serine is involved in covalent substrate amino acid binding at each reaction center of gramicidin S synthetase.

1 reference

12 December 2020

The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: mechanistic and crystallographic evidence for stereospecific alkylation by (R)-alpha-phenylglycidate

1 reference

12 December 2020

Three-dimensional structure of acyl carrier protein determined by NMR pseudoenergy and distance geometry calculations.

1 reference

12 December 2020

Understanding the rates of certain enzyme-catalyzed reactions: proton abstraction from carbon acids, acyl-transfer reactions, and displacement reactions of phosphodiesters

1 reference

12 December 2020

Classes of aminoacyl-tRNA synthetases and the establishment of the genetic code

1 reference

12 December 2020

Arrangement of Catalytic Sites in the Multifunctional Enzyme Enniatin Synthetase

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12 December 2020

Polyphosphate and trimetaphosphate formation under potentially prebiotic conditions.

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12 December 2020

Multidomain enzymes involved in peptide synthesis

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12 December 2020

A common topology of proteins catalyzing ATP-triggered reactions

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12 December 2020

The Complete Amino Acid Sequence of the Acyl Carrier Protein of Escherichia coli

1 reference

12 December 2020

A possible prebiotic synthesis of pantetheine, a precursor to coenzyme A.

1 reference

12 December 2020

Nucleotide sequence of 5' portion of srfA that contains the region required for competence establishment in Bacillus subtilus

1 reference

12 December 2020

Four homologous domains in the primary structure of GrsB are related to domains in a superfamily of adenylate-forming enzymes

1 reference

12 December 2020

Crystal structure of adenylosuccinate synthetase from Escherichia coli. Evidence for convergent evolution of GTP-binding domains

1 reference

12 December 2020

Engineered biosynthesis of novel polyketides

1 reference

12 December 2020

Nucleotide sequence of the Escherichia coli entE gene

1 reference

12 December 2020

Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, the multienzyme integrating the four primary reactions in beta-lactam biosynthesis, as a model peptide synthetase.

1 reference

12 December 2020

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

1 reference

12 December 2020

Cognition, mechanism, and evolutionary relationships in aminoacyl-tRNA synthetases

1 reference

12 December 2020

Cell-free biosynthesis of surfactin, a cyclic lipopeptide produced by Bacillus subtilis

1 reference

12 December 2020

Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases

1 reference

12 December 2020

Three Conserved Glycine Residues in Valine Activation of Gramicidin S Synthetase 2 from Bacillus brevis

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12 December 2020

Detection of 4'-phosphopantetheine at the thioester binding site for L-valine of gramicidinS synthetase 2

1 reference

12 December 2020

1 reference

12 December 2020

The ATP binding site of the yeast plasma membrane proton-translocating ATPase

1 reference

12 December 2020

Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin

1 reference

12 December 2020

Nucleotide binding by multienzyme peptide synthetases

1 reference

12 December 2020

The molecular evolution of genes and proteins: a tale of two serines

1 reference

12 December 2020

Modular structure of genes encoding multifunctional peptide synthetases required for non-ribosomal peptide synthesis

1 reference

12 December 2020

The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame

1 reference

12 December 2020

Gramicidin S biosynthesis operon containing the structural genes grsA and grsB has an open reading frame encoding a protein homologous to fatty acid thioesterases

1 reference

12 December 2020

Three-dimensional structure of acyl carrier protein in solution determined by nuclear magnetic resonance and the combined use of dynamical simulated annealing and distance geometry.

1 reference

12 December 2020

Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage

1 reference

12 December 2020

Expression of an active adenylate-forming domain of peptide synthetases corresponding to acyl-CoA-synthetases.

1 reference

12 December 2020

DNA sequence of Rhizobium trifolii nodulation genes reveals a reiterated and potentially regulatory sequence preceding nodABC and nodFE

1 reference

12 December 2020

Aminoacyl-tRNA synthetase family from prokaryotes and eukaryotes: structural domains and their implications

1 reference

12 December 2020

Structural and functional organization of the surfactin synthetase multienzyme system.

1 reference

12 December 2020

A production of amino acids under possible primitive earth conditions

1 reference

12 December 2020

Modular organization of genes required for complex polyketide biosynthesis

1 reference

12 December 2020

Complete nucleotide sequence of the tycA gene coding the tyrocidine synthetase 1 from Bacillus brevis

1 reference

12 December 2020

Pantetheine-linked peptide intermediates in gramicidin S and tyrocidine biosynthesis

1 reference

12 December 2020

Entire nucleotide sequence for Bacillus brevis Nagano Grs2 gene encoding gramicidin S synthetase 2: a multifunctional peptide synthetase

1 reference

12 December 2020

A small, discrete acyl carrier protein is involved in de novo fatty acid biosynthesis in Streptomyces erythraeus.

1 reference

12 December 2020

Characterization and location of the L-proline activating fragment from the multifunctional gramicidin S synthetase 2

1 reference

12 December 2020

6-Deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme

1 reference

12 December 2020

The P-loop--a common motif in ATP- and GTP-binding proteins

1 reference

12 December 2020

Multienzymatic non ribosomal peptide biosynthesis: identification of the functional domains catalysing peptide elongation and epimerisation

1 reference

12 December 2020

Analysis of surfactin synthetase subunits in srfA mutants of Bacillus subtilis OKB105.

1 reference

12 December 2020

Nucleotide sequence analysis reveals linked N-acetyl hydrolase, thioesterase, transport, and regulatory genes encoded by the bialaphos biosynthetic gene cluster of Streptomyces hygroscopicus

1 reference

12 December 2020

The structure of Ras protein: a model for a universal molecular switch

1 reference

12 December 2020

The fadD gene of Escherichia coli K12 is located close to rnd at 39.6 min of the chromosomal map and is a new member of the AMP-binding protein family

1 reference

12 December 2020

Analysis of core sequences in the D-Phe activating domain of the multifunctional peptide synthetase TycA by site-directed mutagenesis

1 reference

12 December 2020

Bioactive peptide analogs: in vivo and in vitro production

1 reference

12 December 2020

Making connections: RNA-dependent amino acid recognition

1 reference

12 December 2020

The molecular biology of multidomain proteins. Selected examples

1 reference

12 December 2020

Isolation of a Peptidyl-Pantetheine-Protein from Tyrocidine-Synthesizing Polyenzymes

1 reference

12 December 2020

Gene expression in Streptomyces: Construction and application of promoter-probe plasmid vectors in Streptomyces lividans

1 reference

12 December 2020

Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase

1 reference

12 December 2020

Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis

1 reference

12 December 2020

Biosynthesis of the Escherichia coli siderophore enterobactin: sequence of the entF gene, expression and purification of EntF, and analysis of covalent phosphopantetheine

1 reference

12 December 2020

Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. Molecular characterization of the acvA gene encoding the first enzyme of the penicillin biosynthetic pathway

1 reference

12 December 2020

Enzymes in the D-alanine branch of bacterial cell wall peptidoglycan assembly

1 reference

12 December 2020

Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits

1 reference

12 December 2020

Mechanism of cyclosporin A biosynthesis. Evidence for synthesis via a single linear undecapeptide precursor.

1 reference

12 December 2020

On the domain construction of the multienzyme gramicidin S synthetase 2. Isolation of domains activating valine and leucine

1 reference

12 December 2020

Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/J.1460-2075.1989.TB08413.X

Identifiers

DOI

10.1007/BF00807324

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29 February 2020

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