Anti-TNF-alpha loss of response is associated with a decreased percentage of FoxP3+ T cells and a variant NOD2 genotype in patients with Crohn's disease (Q86264935)

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scientific article published on 11 December 2014

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English	Anti-TNF-alpha loss of response is associated with a decreased percentage of FoxP3+ T cells and a variant NOD2 genotype in patients with Crohn's disease	scientific article published on 11 December 2014

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scholarly article

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24 February 2020

Anti-TNF-alpha loss of response is associated with a decreased percentage of FoxP3+ T cells and a variant NOD2 genotype in patients with Crohn's disease (English)

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24 February 2020

Crohn's disease

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based on heuristic

inferred from title

4

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24 February 2020

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24 February 2020

José M González-Navajas

9

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24 February 2020

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Oriol Juanola

1

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24 February 2020

Alba Moratalla

2

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24 February 2020

Ana Gutiérrez

3

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24 February 2020

Paula Giménez

6

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24 February 2020

Isabel Almenta

7

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24 February 2020

Gloria Peiró

8

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24 February 2020

José F Such

10

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24 February 2020

Rubén Francés

11

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24 February 2020

publication date

11 December 2014

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24 February 2020

Journal of Gastroenterology

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24 February 2020

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24 February 2020

7

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24 February 2020

758-768

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24 February 2020

Optimizing immunomodulators and anti-TNF agents in the therapy of Crohn disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AGA technical review on perianal Crohn’s disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal changes of Foxp3 expression in blood and intestinal mucosa in IBD patients responding to infliximab.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review article: Infliximab therapy for inflammatory bowel disease--seven years on

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory Bowel Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of PI3K/Akt/mTOR signaling pathway triggered by PTEN downregulation in the pathogenesis of Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered immunoregulatory profile during anti-tumour necrosis factor treatment of patients with inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral regulatory T cells and serum transforming growth factor-β: relationship with clinical response to infliximab in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy with anti-TNFα antibody enhances number and function of Foxp3+ regulatory T cells in inflammatory bowel diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From symptom to diagnosis: clinical distinctions among various forms of intestinal inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of Immunogenicity on the Long-Term Efficacy of Infliximab in Crohn's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perianal Crohn disease: predictors of need for permanent diversion

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis of regulatory T lymphocytes is increased in chronic inflammatory bowel disease and reversed by anti-TNFα treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review article: Causative factors and the clinical management of patients with Crohn's disease who lose response to anti-TNF-α therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review article: loss of response to anti-TNF treatments in Crohn’s disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXP3 regulates TLR10 expression in human T regulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and biological consequences of immunization to infliximab in pediatric Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXP3⁺ T regulatory cell modifications in inflammatory bowel disease patients treated with anti-TNFα agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CARD15 genotype-phenotype relationships in a small inflammatory bowel disease population with severe disease affection status

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New IBD genetics: common pathways with other diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn's disease is affected by NOD2/CARD15 genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to stricturing disease and higher rate of surgical recurrence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXP3+ regulatory T cells in the human immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety and efficacy of antigen-specific regulatory T-cell therapy for patients with refractory Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine association with bacterial DNA in serum of patients with inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T-Cell Therapy for Crohn's Disease: In Vivo Veritas

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25500977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00535-014-1020-5

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25500977%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25500977%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

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