Differential Effects of the Swedish Mutant Amyloid Precursor Protein on β-Amyloid Accumulation and Secretion in Neurons and Nonneuronal Cells (Q73956014)

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scientific article published on December 19, 1997

Language	Label	Description	Also known as
English	Differential Effects of the Swedish Mutant Amyloid Precursor Protein on β-Amyloid Accumulation and Secretion in Neurons and Nonneuronal Cells	scientific article published on December 19, 1997

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405428%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Differential effects of the swedish mutant amyloid precursor protein on beta-amyloid accumulation and secretion in neurons and nonneuronal cells (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405428%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Differential Effects of the Swedish Mutant Amyloid Precursor Protein on β-Amyloid Accumulation and Secretion in Neurons and Nonneuronal Cells (English)

1 reference

10.1074/JBC.272.51.32247

https://api.crossref.org/works/10.1074/JBC.272.51.32247

29 November 2024

author name string

M. S. Forman

1

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Europe PubMed Central

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29 November 2024

D. G. Cook

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9405428

29 November 2024

S. Leight

3

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29 November 2024

R. W. Doms

4

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29 November 2024

V. M. Lee

5

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29 November 2024

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publication date

1 December 1997

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8 November 2019

19 December 1997

1 reference

National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9405428

29 November 2024

number of pages

7

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full work available at URL

http://www.jbc.org/content/272/51/32247.full.pdf

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Europe PubMed Central

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29 November 2024

https://api.elsevier.com/content/article/PII:S0021925818397564?httpAccept=text/xml

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10.1074/JBC.272.51.32247

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29 November 2024

https://api.elsevier.com/content/article/PII:S0021925818397564?httpAccept=text/plain

1 reference

10.1074/JBC.272.51.32247

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29 November 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.272.51.32247

1 reference

10.1074/JBC.272.51.32247

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29 November 2024

Journal of Biological Chemistry

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8 November 2019

272

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8 November 2019

51

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8 November 2019

32247-32253

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405428%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Altered structural proteins in plaques and tangles: what do they tell us about the biology of Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Relationship between plaques, tangles, and dystrophic processes in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Beta-amyloid precursor protein cleavage by a membrane-bound protease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Intracellular accumulation of beta-amyloid in cells expressing the Swedish mutant amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Enhanced release of amyloid beta-protein from codon 670/671 "Swedish" mutant beta-amyloid precursor protein occurs in both secretory and endocytic pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Alzheimer's Aβ(1–42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Altered cleavage and secretion of a recombinant beta-APP bearing the Swedish familial Alzheimer's disease mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

A new generation of animal cell expression vectors based on the Semliki Forest virus replicon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Increased beta-amyloid release and levels of amyloid precursor protein (APP) in fibroblast cell lines from family members with the Swedish Alzheimer's disease APP670/671 mutation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Intracellular generation of amyloid beta-protein from amyloid beta-protein precursor fragment by direct cleavage with beta- and gamma-secretase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Missense mutations associated with familial Alzheimer's disease in Sweden lead to the production of the amyloid peptide without internalization of its precursor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

beta-Amyloid precursor protein isoforms show correlations with neurones but not with glia of demented subjects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32247

21 January 2018

Role of the beta-amyloid protein in Alzheimer's disease.

10

1 reference

10.1074/JBC.272.51.32247

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29 November 2024

Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons

39

1 reference

10.1074/JBC.272.51.32247

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29 November 2024

Expression of foreign proteins in a human neuronal system

40

1 reference

10.1074/JBC.272.51.32247

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29 November 2024

Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence

43

1 reference

10.1074/JBC.272.51.32247

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29 November 2024

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons

44

1 reference

10.1074/JBC.272.51.32247

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29 November 2024

Identifiers

10.1074/JBC.272.51.32247

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405428%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405428%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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