The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both? (Q73179332)

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1 November 2019

title

The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both? (English)

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1 November 2019

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D C Samuels

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1 November 2019

S L White

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1 November 2019

H M Dahl

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1 November 2019

D M Turnbull

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1 November 2019

R N Lightowlers

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1 November 2019

N Howell

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1 November 2019

publication date

1 November 2000

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1 November 2019

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1 November 2019

volume

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1 November 2019

issue

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1 November 2019

page(s)

500-505

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Molecular genetic aspects of human mitochondrial disorders

1 November 2019

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Mitochondrial DNA mutations at nucleotide 8993 show a lack of tissue- or age-related variation

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Molecular pathology of MELAS and MERRF. The relationship between mutation load and clinical phenotypes

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Genetic counseling and prenatal diagnosis for the mitochondrial DNA mutations at nucleotide 8993

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Mitochondrial genetics '98 is the bottleneck cracked?

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Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.

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Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice

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Number of mitochondria and some properties of mitochondrial DNA in the mouse egg

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Amounts of mitochondrial DNA and abundance of some mitochondrial gene transcripts in early mouse embryos

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A quantitative and cytological study of germ cells in human ovaries

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Heteroplasmy levels of a mitochondrial gene mutation associated with diabetes mellitus decrease in leucocyte DNA upon aging

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7 January 2021

Progressive increase of the mutated mitochondrial DNA fraction in Kearns-Sayre syndrome

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7 January 2021

Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy

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Relaxed replication of mtDNA: A model with implications for the expression of disease

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7 January 2021

Longitudinal analysis of the segregation of mtDNA mutations in heteroplasmic individuals

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7 January 2021

Gonadal dysfunction in mitochondrial encephalomyopathies

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MELAS and MERRF. The relationship between maternal mutation load and the frequency of clinically affected offspring

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The bottleneck: mitochondrial imperatives in oogenesis and ovarian follicular fate

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7 January 2021

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

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7 January 2021

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

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7 January 2021

Mutation in the mitochondrial tRNA(leu) at position 3243 and spontaneous abortions in Japanese women attending a clinic for diabetic pregnancies.

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7 January 2021

Strongly succinate dehydrogenase-reactive blood vessels in muscles from patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes

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7 January 2021

Clinical features, investigation, and management of patients with defects of mitochondrial DNA.

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7 January 2021

Mitochondria and germ-cell death

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7 January 2021

The epidemiology of pathogenic mitochondrial DNA mutations

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7 January 2021

74th ENMC international workshop: mitochondrial diseases 19-20 november 1999, Naarden, the netherlands

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7 January 2021

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Identifiers

DOI

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1 November 2019

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