Vascular endothelial growth factor C (Q7916457)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

• Flt4-L
• vascular endothelial growth factor C
• vascular endothelial growth factor-related protein
• VRP
• FLT4 ligand DHM
• Flt4 ligand
• VEGFC

edit

Language	Label	Description	Also known as
English	Vascular endothelial growth factor C	mammalian protein found in Homo sapiens	Flt4-L vascular endothelial growth factor C vascular endothelial growth factor-related protein VRP FLT4 ligand DHM Flt4 ligand VEGFC

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P49767

part of

Cystine-knot cytokine

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49767

Putative uncharacterized transport proteins

1 reference

Transporter Classification Database ID

9.B.88.2.1

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

PDGF/VEGF domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CXCXC repeat domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Platelet-derived growth factor, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P49767

encoded by

VEGFC

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P49767

molecular function

chemoattractant activity

determination method or standard

IDA

1 reference

retrieved

24 April 2018

stated in

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49767&geneProductId=UniProtKB:P49767

determination method or standard

IDA

protein binding

determination method or standard

IPI

2 references

retrieved

8 April 2019

stated in

Structural determinants of growth factor binding and specificity by VEGF receptor 2

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IPI

retrieved

8 April 2019

stated in

Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IPI

growth factor activity

determination method or standard

IBA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

vascular endothelial growth factor receptor 3 binding

determination method or standard

IBA

IEA

IPI

3 references

retrieved

8 April 2019

stated in

Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IPI

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

chemoattractant activity

determination method or standard

IBA

IDA

2 references

retrieved

8 April 2019

stated in

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

vascular endothelial growth factor receptor binding

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

cell component

extracellular region

determination method or standard

TAS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

platelet alpha granule lumen

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

TAS

extracellular space

determination method or standard

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

biological process

negative regulation of cell population proliferation

determination method or standard

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49767&geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of neuroblast proliferation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of protein secretion

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

substrate-dependent cell migration

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

TAS

signal transduction

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

TAS

positive regulation of protein autophosphorylation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

multicellular organism development

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

morphogenesis of embryonic epithelium

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of cell-matrix adhesion

determination method or standard

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49767&geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of mast cell chemotaxis

determination method or standard

IDA

1 reference

retrieved

24 April 2018

stated in

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49767&geneProductId=UniProtKB:P49767

determination method or standard

IDA

positive regulation of blood vessel endothelial cell migration

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of cell division

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

induction of positive chemotaxis

determination method or standard

IDA

1 reference

retrieved

24 April 2018

stated in

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49767&geneProductId=UniProtKB:P49767

determination method or standard

IDA

platelet degranulation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

TAS

positive regulation of peptidyl-tyrosine phosphorylation

determination method or standard

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49767&geneProductId=UniProtKB:P49767

determination method or standard

IEA

negative regulation of blood pressure

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of cell population proliferation

determination method or standard

TAS

IEA

2 references

retrieved

8 April 2019

stated in

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of lymphangiogenesis

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

regulation of vascular endothelial growth factor receptor signaling pathway

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

cell differentiation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of epithelial cell proliferation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

animal organ morphogenesis

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive chemotaxis

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

angiogenesis

determination method or standard

IBA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

response to hypoxia

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

positive regulation of endothelial cell proliferation

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

positive regulation of angiogenesis

determination method or standard

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

cellular response to leukemia inhibitory factor

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

vascular endothelial growth factor receptor signaling pathway

determination method or standard

IBA

IDA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

retrieved

8 April 2019

stated in

Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

regulation of signaling receptor activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IEA

positive regulation of protein phosphorylation

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

sprouting angiogenesis

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

vascular endothelial growth factor signaling pathway

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

induction of positive chemotaxis

determination method or standard

IBA

IDA

2 references

retrieved

8 April 2019

stated in

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

positive regulation of mast cell chemotaxis

determination method or standard

IBA

IDA

2 references

retrieved

8 April 2019

stated in

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

GOA

curator

UniProt

UniProt protein ID

P49767

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49767

determination method or standard

IBA

Gene Atlas image

PBB GE VEGFC 209946 at fs.png
732 × 530; 11 KB

0 references

has part(s)

CXCXC repeat

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49767

Platelet-derived growth factor, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49767

PDGF/VEGF domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P49767

Commons category

VEGF-C

0 references

Identifiers

MeSH descriptor ID

D042582

subject named as

Vascular Endothelial Growth Factor C

0 references

MeSH tree code

D12.644.276.100.800.400

0 references

D12.776.467.100.800.400

0 references

D23.529.100.800.400

0 references

RefSeq protein ID

NP_005420

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7424

UniProt protein ID

P49767

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P49767

Ensembl protein ID

ENSP00000480043

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000480043

Freebase ID

/m/03c_rfy

0 references

Microsoft Academic ID

103041312

0 references

OpenAlex ID

C103041312

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

2X1W

1 reference

stated in

UniProt

UniProt protein ID

P49767

retrieved

9 August 2016

language of work or name

English

2X1X

1 reference

stated in

UniProt

UniProt protein ID

P49767

retrieved

9 August 2016

language of work or name

English

4BSK

1 reference

stated in

UniProt

UniProt protein ID

P49767

retrieved

9 August 2016

language of work or name

English

Transporter Classification Database ID

9.B.88.2.1

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

UMLS CUI

C0388911

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(5 entries)

edit

• cywiki VEGFC
• dewiki VEGF-C
• enwiki Vascular endothelial growth factor C
• fiwiki VEGF-C
• ukwiki VEGFC

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(1 entry)

edit

• commonswiki Category:VEGF-C

Retrieved from "https://www.wikidata.org/w/index.php?title=Q7916457&oldid=2022910917"