Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells (Q64280942)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

title

Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

author name string

Jaigeeth Deveryshetty

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Thibaut Peterlini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Mikhail Ryzhikov

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Nadine Brahiti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Jean-Yves Masson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

language of work or name

English

0 references

publication date

29 April 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

12 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6533086/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Structure of helical RecA-DNA complexes. Complexes formed in the presence of ATP-gamma-S or ATP.

1 reference

12 December 2020

Protein interactions in genetic recombination in Escherichia coli. Interactions involving RecO and RecR overcome the inhibition of RecA by single-stranded DNA-binding protein

1 reference

12 December 2020

Purification and characterization of the Escherichia coli RecO protein. Renaturation of complementary single-stranded DNA molecules catalyzed by the RecO protein.

1 reference

12 December 2020

Recombinant replication protein A: expression, complex formation, and functional characterization

1 reference

12 December 2020

Biochemical interaction of the Escherichia coli RecF, RecO, and RecR proteins with RecA protein and single-stranded DNA binding protein

1 reference

12 December 2020

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

12 December 2020

Function of Yeast Rad52 Protein as a Mediator between Replication Protein A and the Rad51 Recombinase

1 reference

12 December 2020

Synergistic actions of Rad51 and Rad52 in recombination and DNA repair

1 reference

12 December 2020

Stimulation by Rad52 of yeast Rad51-mediated recombination

1 reference

12 December 2020

Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A

1 reference

12 December 2020

The function of the secondary DNA-binding site of RecA protein during DNA strand exchange

1 reference

12 December 2020

Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing

1 reference

12 December 2020

RecA binding to a single double-stranded DNA molecule: a possible role of DNA conformational fluctuations

1 reference

12 December 2020

RMPs: recombination/replication mediator proteins

1 reference

12 December 2020

RecA protein-dependent R-loop formation in vitro.

1 reference

12 December 2020

The breast cancer susceptibility gene, BRCA2: at the crossroads between DNA replication and recombination?

1 reference

12 December 2020

A novel pairing process promoted by Escherichia coli RecA protein: inverse DNA and RNA strand exchange

1 reference

12 December 2020

Basis for avid homologous DNA strand exchange by human Rad51 and RPA.

1 reference

12 December 2020

BRCA2 is required for homology-directed repair of chromosomal breaks

1 reference

12 December 2020

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

1 reference

12 December 2020

Direct DNA binding by Brca1

1 reference

12 December 2020

Comparison of bacteriophage T4 UvsX and human Rad51 filaments suggests that RecA-like polymers may have evolved independently.

1 reference

12 December 2020

Biallelic inactivation of BRCA2 in Fanconi anemia

1 reference

12 December 2020

Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation

1 reference

12 December 2020

Interaction with Rad51 is indispensable for recombination mediator function of Rad52.

1 reference

12 December 2020

Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form

1 reference

12 December 2020

Structure of the single-strand annealing domain of human RAD52 protein

1 reference

12 December 2020

Escherichia coli RecO protein anneals ssDNA complexed with its cognate ssDNA-binding protein: A common step in genetic recombination

1 reference

12 December 2020

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

1 reference

12 December 2020

RecFOR proteins load RecA protein onto gapped DNA to accelerate DNA strand exchange: a universal step of recombinational repair

1 reference

12 December 2020

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

1 reference

12 December 2020

Functional evaluation and cancer risk assessment of BRCA2 unclassified variants

1 reference

12 December 2020

Cancer: catalyst of a catalyst

1 reference

12 December 2020

Functional assays for replication protein A (RPA).

1 reference

12 December 2020

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

1 reference

12 December 2020

Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.

1 reference

12 December 2020

Regulation of bacterial RecA protein function

1 reference

12 December 2020

Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase.

1 reference

12 December 2020

Molecular anatomy of the recombination mediator function of Saccharomyces cerevisiae Rad52.

1 reference

12 December 2020

DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair

1 reference

12 December 2020

Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures

1 reference

12 December 2020

Interaction with RPA is necessary for Rad52 repair center formation and for its mediator activity

1 reference

12 December 2020

RecFOR and RecOR as distinct RecA loading pathways

1 reference

12 December 2020

Second-end capture in DNA double-strand break repair promoted by Brh2 protein of Ustilago maydis

1 reference

12 December 2020

Rad52 promotes second-end DNA capture in double-stranded break repair to form complement-stabilized joint molecules

1 reference

12 December 2020

PALB2 links BRCA1 and BRCA2 in the DNA-damage response

1 reference

12 December 2020

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

1 reference

12 December 2020

PALB2 regulates recombinational repair through chromatin association and oligomerization

1 reference

12 December 2020

MRG15 is a novel PALB2-interacting factor involved in homologous recombination

1 reference

12 December 2020

PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2.

1 reference

12 December 2020

Structural basis for recruitment of BRCA2 by PALB2

1 reference

12 December 2020

How the fanconi anemia pathway guards the genome

1 reference

12 December 2020

Human Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52-ssDNA complexes

1 reference

12 December 2020

MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks

1 reference

12 December 2020

Purified human BRCA2 stimulates RAD51-mediated recombination

1 reference

12 December 2020

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

1 reference

12 December 2020

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

1 reference

12 December 2020

Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination

1 reference

12 December 2020

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.

1 reference

12 December 2020

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping

1 reference

12 December 2020

Vital roles of the second DNA-binding site of Rad52 protein in yeast homologous recombination

1 reference

12 December 2020

Mechanism of RecO recruitment to DNA by single-stranded DNA binding protein

1 reference

12 December 2020

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

1 reference

12 December 2020

Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.

1 reference

12 December 2020

ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair

1 reference

12 December 2020

Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.

1 reference

12 December 2020

PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function

1 reference

12 December 2020

PALB2 self-interaction controls homologous recombination

1 reference

12 December 2020

Structural studies of SSB interaction with RecO.

1 reference

12 December 2020

Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA

1 reference

12 December 2020

A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activity

1 reference

12 December 2020

A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing

1 reference

12 December 2020

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

1 reference

12 December 2020

Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks

1 reference

12 December 2020

Cancer suppression by the chromosome custodians, BRCA1 and BRCA2.

1 reference

12 December 2020

Exploring the roles of PALB2 at the crossroads of DNA repair and cancer.

1 reference

12 December 2020

PALB2: the hub of a network of tumor suppressors involved in DNA damage responses

1 reference

12 December 2020

RecO protein initiates DNA recombination and strand annealing through two alternative DNA binding mechanisms.

1 reference

12 December 2020

Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination

1 reference

12 December 2020

Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins

1 reference

12 December 2020

Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry

1 reference

12 December 2020

Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing

1 reference

12 December 2020

A mechanism for the suppression of homologous recombination in G1 cells

1 reference

12 December 2020

Advances in structural studies of recombination mediator proteins

1 reference

12 December 2020

Coupling of Homologous Recombination and the Checkpoint by ATR.

1 reference

12 December 2020

Cancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motif

1 reference

12 December 2020

A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.

1 reference

12 December 2020

Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination

1 reference

12 December 2020

Rad52 Inverse Strand Exchange Drives RNA-Templated DNA Double-Strand Break Repair

1 reference

12 December 2020

MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress.

1 reference

12 December 2020

BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing

1 reference

12 December 2020

Antiparallel Coiled-Coil Interactions Mediate Homodimerization of the DNA Damage Repair Protein, PALB2

1 reference

12 December 2020

The Tumor Suppressor PALB2: Inside Out

1 reference

12 December 2020

BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.44063

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

31017574

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31017574%20AND%20SRC:MED&resulttype=core&format=json