Curcumin regulates the miR-21/PTEN/Akt pathway and acts in synergy with PD98059 to induce apoptosis of human gastric cancer MGC-803 cells (Q64268219)

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scientific article published on 06 February 2019

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English	Curcumin regulates the miR-21/PTEN/Akt pathway and acts in synergy with PD98059 to induce apoptosis of human gastric cancer MGC-803 cells	scientific article published on 06 February 2019

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

title

Curcumin regulates the miR-21/PTEN/Akt pathway and acts in synergy with PD98059 to induce apoptosis of human gastric cancer MGC-803 cells (English)

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stated in

Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

main subject

curcumin

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stomach neoplasm

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author

Zhanrong Qiang

series ordinal

1

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Wei Hong Sha

series ordinal

6

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

author name string

Lingyu Meng

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2

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Caixia Yi

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3

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Lianying Yu

series ordinal

4

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Wenxia Chen

series ordinal

5

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

language of work or name

English

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publication date

6 February 2019

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

published in

Journal of International Medical Research

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Europe PubMed Central

PMC publication ID

6421392

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

volume

47

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

issue

3

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

page(s)

1288-1297

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Europe PubMed Central

PMC publication ID

6421392

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

copyright license

Creative Commons Attribution-NonCommercial 4.0 International

start time

6 February 2019

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April 2022 Public Data File from Crossref

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copyrighted

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April 2022 Public Data File from Crossref

cites work

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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reference URL

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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Effects of water-soluble antioxidants and MAPKK/MEK inhibitor on curcumin-induced apoptosis in HL-60 human leukemic cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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Chemopreventive properties of curcumin

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PubMed

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microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN

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https://pubmed.ncbi.nlm.nih.gov/30727807

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The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches.

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Carcinoma of the stomach: A review of epidemiology, pathogenesis, molecular genetics and chemoprevention

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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Combination treatment of PD98059 and DAPT in gastric cancer through induction of apoptosis and downregulation of WNT/β-catenin

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Difluorinated-curcumin (CDF) restores PTEN expression in colon cancer cells by down-regulating miR-21

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Therapeutic implications of curcumin in the prevention of diabetic retinopathy via modulation of anti-oxidant activity and genetic pathways

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Her3 is associated with poor survival of gastric adenocarcinoma: Her3 promotes proliferation, survival and migration of human gastric cancer mediated by PI3K/AKT signaling pathway

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

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12 December 2020

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Prognostic role of microRNA-21 in gastric cancer: a meta-analysis

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Enhancing anti-inflammation activity of curcumin through O/W nanoemulsions

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Mitogen-activated protein kinase signaling pathway and invasion and metastasis of gastric cancer

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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The critical roles of miR-21 in anti-cancer effects of curcumin

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Inhibition of MAPK signaling pathways enhances cell death induced by 5-Aminolevulinic acid-photodynamic therapy in skin squamous carcinoma cells

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Curcumin inhibits HIV-1 by promoting Tat protein degradation

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Upstream and Downstream Co-inhibition of Mitogen-Activated Protein Kinase and PI3K/Akt/mTOR Pathways in Pancreatic Ductal Adenocarcinoma

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https://pubmed.ncbi.nlm.nih.gov/30727807

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Molecular targets of curcumin for cancer therapy: an updated review.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30727807

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12 December 2020

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Curcumin Inhibits Gastric Carcinoma Cell Growth and Induces Apoptosis by Suppressing the Wnt/β-Catenin Signaling Pathway.

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https://pubmed.ncbi.nlm.nih.gov/30727807

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A Comprehensive Review on Pharmacotherapeutics of Three Phytochemicals, Curcumin, Quercetin, and Allicin, in the Treatment of Gastric Cancer.

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Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials

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miR-21 Inhibitors Modulate Biological Functions of Gastric Cancer Cells via PTEN/PI3K/mTOR Pathway

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Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

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Identifiers

DOI

10.1177/0300060518822213

1 reference

stated in

Europe PubMed Central

PMC publication ID

6421392

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

PMC publication ID

6421392

1 reference

stated in

Europe PubMed Central

PMC publication ID

6421392

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

PubMed publication ID

30727807

1 reference

stated in

Europe PubMed Central

PMC publication ID

6421392

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30727807%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

 

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