LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway (Q64245246)

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scientific article published on 24 January 2019

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English	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway	scientific article published on 24 January 2019

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25 April 2020

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway (English)

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25 April 2020

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hepatocellular carcinoma

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13

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Yin-Li Zheng

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Lei Li

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Yong-Xun Jia

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Bao-Zhu Zhang

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Jiang-Chao Li

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Ying-Hui Zhu

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Meng-Qing Li

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Jiao-Zi He

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Ting-Ting Zeng

9

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Xiao-Jiao Ban

10

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Yun-Fei Yuan

11

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25 April 2020

Yan Li

12

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24 January 2019

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3

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796-810

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Why do cancers have high aerobic glycolysis?

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Application of comparative functional genomics to identify best-fit mouse models to study human cancer

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The ubiquitin-proteasome system and its role in inflammatory and autoimmune diseases

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Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

1 reference

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

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Long non-coding RNAs: insights into functions

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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

1 reference

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

1 reference

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Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

1 reference

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Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

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12 December 2020

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Molecular mechanisms of long noncoding RNAs

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https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

based on heuristic

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Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma.

1 reference

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12 December 2020

based on heuristic

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miRNA regulates noncoding RNA: a noncanonical function model

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

based on heuristic

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The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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Xist RNA is a potent suppressor of hematologic cancer in mice

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https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect

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https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

based on heuristic

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PKM2 regulates chromosome segregation and mitosis progression of tumor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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The multilayered complexity of ceRNA crosstalk and competition

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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An update on LNCipedia: a database for annotated human lncRNA sequences.

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https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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The long intergenic noncoding RNA UFC1, a target of MicroRNA 34a, interacts with the mRNA stabilizing protein HuR to increase levels of β-catenin in HCC cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-activating factor receptor-mediated PI3K/AKT activation contributes to the malignant development of esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cancer statistics, 2012

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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Unique features of long non-coding RNA biogenesis and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-365a-3p promotes tumor growth and metastasis in laryngeal squamous cell carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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inferred from PubMed ID database lookup

Linking Long Noncoding RNA Localization and Function

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Comparison of hepatocellular carcinoma in Eastern versus Western populations.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1.

1 reference

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12 December 2020

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1 reference

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GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses.

1 reference

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12 December 2020

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Long non-coding RNA PVT1 promotes glycolysis and tumor progression by regulating miR-497/HK2 axis in osteosarcoma.

1 reference

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12 December 2020

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Human hepatic gene expression signature of non-alcoholic fatty liver disease progression, a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30809309

12 December 2020

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10.7150/THNO.28992

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