Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting (Q64236077)

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scientific article published on 22 January 2019

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English	Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting	scientific article published on 22 January 2019

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scholarly article

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Europe PubMed Central

PMC publication ID

6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

title

Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting (English)

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stated in

Europe PubMed Central

PMC publication ID

6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

main subject

Biological Sciences

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author

Annemieke Aartsma-Rus

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7

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Europe PubMed Central

PMC publication ID

6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Benedikt M. Kessler

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9

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Europe PubMed Central

PMC publication ID

6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

author name string

Cyriel S Olie

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1

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Europe PubMed Central

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6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Muhammad Riaz

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2

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6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Rebecca Konietzny

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3

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Europe PubMed Central

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6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Philip D Charles

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4

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Europe PubMed Central

PMC publication ID

6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Adan Pinto-Fernandez

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5

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6370712

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22 April 2020

Szymon M Kiełbasa

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6

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6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Jelle J Goeman

series ordinal

8

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6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

Vered Raz

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10

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Europe PubMed Central

PMC publication ID

6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

language of work or name

English

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publication date

22 January 2019

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Europe PubMed Central

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6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

volume

12

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Europe PubMed Central

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6370712

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

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22 April 2020

page(s)

318-332

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6370712

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22 April 2020

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reference URL

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Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1.

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Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres

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Modeling oculopharyngeal muscular dystrophy in myotube cultures reveals reduced accumulation of soluble mutant PABPN1 protein

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The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites.

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PubMed

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12 December 2020

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Sirtuin activators and inhibitors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30739015

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12 December 2020

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Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30739015

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12 December 2020

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Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns

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12 December 2020

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12 December 2020

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PABPN1: molecular function and muscle disease

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12 December 2020

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A decline in PABPN1 induces progressive muscle weakness in oculopharyngeal muscle dystrophy and in muscle aging

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12 December 2020

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Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy

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https://pubmed.ncbi.nlm.nih.gov/30739015

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SIRT1 and other sirtuins in metabolism

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https://pubmed.ncbi.nlm.nih.gov/30739015

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12 December 2020

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A novel feed-forward loop between ARIH2 E3-ligase and PABPN1 regulates aging-associated muscle degeneration

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30739015

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12 December 2020

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Mitochondrial dysfunction reveals the role of mRNA poly(A) tail regulation in oculopharyngeal muscular dystrophy pathogenesis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30739015

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https://pubmed.ncbi.nlm.nih.gov/30739015

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Identification of the Acetylation and Ubiquitin-Modified Proteome during the Progression of Skeletal Muscle Atrophy

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https://pubmed.ncbi.nlm.nih.gov/30739015

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Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training

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Antisense targeting of 3' end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for facioscapulohumeral dystrophy: a new gene-silencing approach

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Mechanisms and Dynamics of Protein Acetylation in Mitochondria.

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PABPN1-Dependent mRNA Processing Induces Muscle Wasting.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30739015

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based on heuristic

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The world of protein acetylation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30739015

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Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics

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The effect of protein acetylation on the formation and processing of inclusion bodies and endogenous protein aggregates in Escherichia coli cells

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Enhanced Protein Translation Underlies Improved Metabolic and Physical Adaptations to Different Exercise Training Modes in Young and Old Humans.

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Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30739015

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Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging.

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It takes two to tango: NAD+ and sirtuins in aging/longevity control

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunctional transcripts are formed by alternative polyadenylation in OPMD.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30739015

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12 December 2020

based on heuristic

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A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline

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12 December 2020

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Identifiers

DOI

10.1016/J.ISCI.2019.01.024

1 reference

stated in

Europe PubMed Central

PMC publication ID

6370712

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

PMC publication ID

6370712

1 reference

stated in

Europe PubMed Central

PMC publication ID

6370712

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

PubMed publication ID

30739015

1 reference

stated in

Europe PubMed Central

PMC publication ID

6370712

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30739015%20AND%20SRC:MED&resulttype=core&format=json

retrieved

22 April 2020

 

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