Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women (Q64110801)

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English	Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women	article

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10 April 2020

Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women (English)

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10 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001917%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001917%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001917%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

2503-2513

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001917%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Association between a CYP3A4 genetic variant and clinical presentation in African-American prostate cancer patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethnic differences in the frequency of prostate cancer susceptibility alleles at SRD5A2 and CYP3A4

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of 26,26,26,27,27,27-F6-1 alpha,23S,25-trihydroxyvitamin D3 by human UDP-glucuronosyltransferase 1A3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Racial Disparity of Epidermal Growth Factor Receptor Expression in Prostate Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Bayesian measure of the probability of false discovery in genetic epidemiology studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of human UDP-glucuronosyltransferases catalyzing hepatic 1alpha,25-dihydroxyvitamin D3 conjugation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of genetic polymorphisms in ovarian cancer susceptibility: development of an international ovarian cancer association consortium

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of vitamin D receptor in the lithocholic acid-mediated CYP3A induction in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D gene pathway polymorphisms and risk of colorectal, breast, and prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovarian cancer risk factors in African-American and white women

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of VDR expression in rat and human intestine and liver--consequences for CYP3A expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new statistic to evaluate imputation reliability

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The therapeutic potential of targeting the EGFR family in epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The coupling of epidermal growth factor receptor down regulation by 1alpha,25-dihydroxyvitamin D3 to the hormone-induced cell cycle arrest at the G1-S checkpoint in ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of GWAS "Hits" by Race for Breast and Prostate Cancers in European Americans and African Americans

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epidermal growth factor receptor as a therapeutic target in epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of CYP3A4 and CYP3A5 expression and modulation of "intracrine" metabolism of androgens in prostate cells by liganded vitamin D receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in tobacco-related cancer susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of UDP-glucuronosyltransferases 2A2 and 2A3 in tobacco carcinogen metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D receptor (VDR) polymorphisms and risk of ovarian cancer in Caucasian and African American women

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global ovarian cancer health disparities

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cigarette smoking and risk of ovarian cancer: a pooled analysis of 21 case-control studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular signatures of epithelial ovarian cancer: analysis of associations with tumor characteristics and epidemiologic risk factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive profiling of EGFR/HER receptors for personalized treatment of gynecologic cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous and exogenous hormone exposure and the risk of meningioma in men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma levels of 25-hydroxyvitamin D3 and in vivo markers of cytochrome P450 3A activity in Swedes and Koreans: effects of a genetic polymorphism and oral contraceptives

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine N-glucuronidation relative to N-oxidation and C-oxidation and UGT2B10 genotype in five ethnic/racial groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D-associated genetic variation and risk of breast cancer in the breast and prostate cancer cohort consortium (BPC3).

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unravelling the transcriptomic landscape of the major phase II UDP-glucuronosyltransferase drug metabolizing pathway using targeted RNA sequencing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D Metabolism Genes in Asthma and Atopy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic Determinants of Vitamin D-Regulated Gene Expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The status of epidermal growth factor receptor in borderline ovarian tumours.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Association Between Body Mass Index and Presenting Symptoms in African American Women with Ovarian Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FastPop: a rapid principal component derived method to infer intercontinental ancestry using genetic data

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GC Gene Polymorphism and Unbound Serum Retinol-Binding Protein 4 Are Related to the Risk of Insulin Resistance in Patients With Chronic Hepatitis C: A Prospective Cross-Sectional Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxylation of 20-hydroxyvitamin D3 by human CYP3A4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity, weight gain, and ovarian cancer risk in African American women

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic disorders of Vitamin D biosynthesis and degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between Body Powder Use and Ovarian Cancer: The African American Cancer Epidemiology Study (AACES)

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2R1 mutations causing vitamin D-deficiency rickets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dairy, calcium, vitamin D and ovarian cancer risk in African-American women

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary inflammatory index and risk of epithelial ovarian cancer in African American women

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of CYP27B1 gene expression in Iranian patients with relapsing-remitting multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP24A1 LOSS OF FUNCTION: CLINICAL PHENOTYPE OF MONOALLELIC AND BIALLELIC MUTATIONS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cigarette smoking and the association with serous ovarian cancer in African American women: African American Cancer Epidemiology Study (AACES).

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide discovery of active regulatory elements and transcription factor footprints in Caenorhabditis elegans using DNase-seq.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing the functional association of intronic miRNAs with their host genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovarian cancer statistics, 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/31001917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/CAM4.1996

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001917%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001917%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001917%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

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