Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer (Q64118233)

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scientific article published on 21 February 2019

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English	Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer	scientific article published on 21 February 2019

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6406812

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25 April 2020

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Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer (English)

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6406812

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25 April 2020

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Adam R Karpf

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4

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6406812

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25 April 2020

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Carter J Barger

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6406812

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25 April 2020

Connor Branick

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2

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6406812

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25 April 2020

Linda Chee

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3

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6406812

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English

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21 February 2019

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6406812

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25 April 2020

published in

Cancers

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6406812

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25 April 2020

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11

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6406812

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2

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25 April 2020

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251

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Creative Commons Attribution 4.0 International

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21 February 2019

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cites work

Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues

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The winged-helix transcription factor Trident is expressed in cycling cells

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The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization

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The Winged-Helix Transcription Factor Trident is Expressed in Actively Dividing Lymphocytes

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The Rb/E2F pathway: expanding roles and emerging paradigms

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FOXM1 is a downstream target of Gli1 in basal cell carcinomas

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High-resolution comparative genomic hybridization detects extra chromosome arm 12p material in most cases of carcinoma in situ adjacent to overt germ cell tumors, but not before the invasive tumor development

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FoxM1 is required for execution of the mitotic programme and chromosome stability

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12 December 2020

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Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c

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12 December 2020

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FoxM1 dances with mitosis

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

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Despite its strong transactivation domain, transcription factor FOXM1c is kept almost inactive by two different inhibitory domains

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

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A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

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Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

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Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

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FoxM1 inhibitors as potential anticancer drugs

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https://pubmed.ncbi.nlm.nih.gov/30795624

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A novel mode of FoxM1 regulation: positive auto-regulatory loop

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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based on heuristic

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FoxM1 is a general target for proteasome inhibitors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-proliferative FoxM1 is a target of p53-mediated repression

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 negatively regulates expression of FoxM1.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

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based on heuristic

inferred from PubMed ID database lookup

Raf/MEK/MAPK Signaling Stimulates the Nuclear Translocation and Transactivating Activity of FOXM1

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

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Integrative genomic profiling reveals conserved genetic mechanisms for tumorigenesis in common entities of non-Hodgkin's lymphoma

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Array-Based Comparative Genomic Hybridization Identifies CDK4 and FOXM1 Alterations as Independent Predictors of Survival in Malignant Peripheral Nerve Sheath Tumor

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Modeling high-grade serous ovarian carcinogenesis from the fallopian tube

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ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance

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Integrated genomic analyses of ovarian carcinoma

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Thiostrepton, proteasome inhibitors and FOXM1.

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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Primary culture and immortalization of human fallopian tube secretory epithelial cells

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Comprehensive molecular portraits of human breast tumours

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https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

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FOX(M1) news--it is cancer

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PubMed

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

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PubMed

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based on heuristic

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Dysregulated expression of FOXM1 isoforms drives progression of pancreatic cancer

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https://pubmed.ncbi.nlm.nih.gov/30795624

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based on heuristic

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TCPA: a resource for cancer functional proteomics data

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

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Pan-cancer patterns of somatic copy number alteration

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXO3a loss is a frequent early event in high-grade pelvic serous carcinogenesis

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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based on heuristic

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Genome engineering using the CRISPR-Cas9 system

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

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Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube-derived high-grade serous ovarian cancers.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXM1c promotes pancreatic cancer epithelial-to-mesenchymal transition and metastasis via upregulation of expression of the urokinase plasminogen activator system

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncovering SUMOylation dynamics during cell-cycle progression reveals FoxM1 as a key mitotic SUMO target protein.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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based on heuristic

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A pan-cancer proteomic perspective on The Cancer Genome Atlas.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

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Improved vectors and genome-wide libraries for CRISPR screening

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

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12 December 2020

based on heuristic

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Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 12p13.33/RAD52 locus and genetic susceptibility to squamous cell cancers of upper aerodigestive tract

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is there potential to target FOXM1 for 'undruggable' lung cancers?

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inference of transcriptional regulation in cancers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXM1 binds directly to non-consensus sequences in the human genome

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic landscape of genes and infiltrating immune cells across human cancers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel FOXM1 isoform, FOXM1D, promotes epithelial-mesenchymal transition and metastasis through ROCKs activation in colorectal cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXM1 allows human keratinocytes to bypass the oncogene-induced differentiation checkpoint in response to gain of MYC or loss of p53.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toil enables reproducible, open source, big biomedical data analyses

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional landscape of human cancers.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene isoforms as expression-based biomarkers predictive of drug response in vitro.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Explore, Visualize, and Analyze Functional Cancer Proteomic Data Using the Cancer Proteome Atlas.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic and Functional Approaches to Understanding Cancer Aneuploidy.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Drivers of Aneuploidy in Breast Tumors.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrated Molecular Characterization of Testicular Germ Cell Tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of FOXM1 as a specific marker for triple‑negative breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30795624

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.3390/CANCERS11020251

1 reference

stated in

Europe PubMed Central

PMC publication ID

6406812

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30795624%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 April 2020

PMC publication ID

6406812

1 reference

stated in

Europe PubMed Central

PMC publication ID

6406812

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30795624%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 April 2020

PubMed publication ID

30795624

1 reference

stated in

Europe PubMed Central

PMC publication ID

6406812

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30795624%20AND%20SRC:MED&resulttype=core&format=json

retrieved

25 April 2020

 

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