Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib (Q64118169)

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scholarly article by Magnus Diller et al published 2019 in Frontiers in Immunology

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Language	Label	Description	Also known as
English	Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib	scholarly article by Magnus Diller et al published 2019 in Frontiers in Immunology

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instance of

scholarly article

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title

Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib (English)

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main subject

peficitinib

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rheumatoid arthritis

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inferred from title

author

Ulf Müller-Ladner

series ordinal

7

object named as

Ulf Müller-Ladner

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author name string

Magnus Diller

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1

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Rebecca Hasseli

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2

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Marie-Lisa Hülser

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3

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Iris Aykara

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4

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Klaus Frommer

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5

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Stefan Rehart

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6

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Elena Neumann

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8

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language of work or name

English

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publication date

2019

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published in

Frontiers in Immunology

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volume

10

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page(s)

541

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copyright license

Creative Commons Attribution 4.0 International

start time

26 March 2019

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stated in

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Concentrations and origins of soluble interleukin 6 receptor-alpha in serum and synovial fluid

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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Soluble interleukin 6 (IL-6) receptor and IL-6 levels in serum and synovial fluid of patients with different arthropathies

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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Transcriptional Roles of CCAAT/Enhancer Binding Protein-β, Nuclear Factor-κB, and C-promoter Binding Factor 1 in Interleukin (IL)-1β-induced IL-6 Synthesis by Human Rheumatoid Fibroblast-like Synoviocytes

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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inferred from PubMed ID database lookup

Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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CP690,550 inhibits oncostatin M-induced JAK/STAT signaling pathway in rheumatoid synoviocytes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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The JAK inhibitor CP-690,550 (tofacitinib) inhibits TNF-induced chemokine expression in fibroblast-like synoviocytes: autocrine role of type I interferon

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 upregulates expression of ADAMTS-4 in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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Inhibition of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signalling pathway in rheumatoid synovial fibroblasts using small molecule compounds

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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The pharmacokinetics, pharmacodynamics, and safety of baricitinib, an oral JAK 1/2 inhibitor, in healthy volunteers.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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Extended-Release Once-Daily Formulation of Tofacitinib: Evaluation of Pharmacokinetics Compared With Immediate-Release Tofacitinib and Impact of Food

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

based on heuristic

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Pharmacokinetics, Pharmacodynamics, and Safety of ASP015K (Peficitinib), a New Janus Kinase Inhibitor, in Healthy Subjects

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

based on heuristic

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Stable activation of fibroblasts in rheumatic arthritis-causes and consequences

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

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12 December 2020

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A novel JAK inhibitor, peficitinib, demonstrates potent efficacy in a rat adjuvant-induced arthritis model

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

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EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of rheumatoid arthritis in the United States adult population in healthcare claims databases, 2004-2014.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Filgotinib, a Selective JAK-1 Inhibitor, After Short-Term Treatment of Rheumatoid Arthritis: Results of Two Randomized Phase IIa Trials

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JAK/STAT Blockade Alters Synovial Bioenergetics, Mitochondrial Function, and Proinflammatory Mediators in Rheumatoid Arthritis

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30984167

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.3389/FIMMU.2019.00541

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PMC publication ID

6448044

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PubMed publication ID

30984167

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