Discovery of fused 5,6-bicyclic heterocycles as γ-secretase modulators (Q53315614)

From Wikidata

Jump to navigation Jump to search

scientific article published on December 13, 2010

edit

Language	Label	Description	Also known as
English	Discovery of fused 5,6-bicyclic heterocycles as γ-secretase modulators	scientific article published on December 13, 2010

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

title

Discovery of fused 5,6-bicyclic heterocycles as γ-secretase modulators (English)

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

author

Lynn A. Hyde

series ordinal

15

object named as

Lynn Hyde

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

author name string

Jun Qin

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Pawan Dhondi

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Xianhai Huang

series ordinal

3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Mihirbaran Mandal

series ordinal

4

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Zhiqiang Zhao

series ordinal

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Dmitri Pissarnitski

series ordinal

6

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Wei Zhou

series ordinal

7

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Robert Aslanian

series ordinal

8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Zhaoning Zhu

series ordinal

9

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

William Greenlee

series ordinal

10

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

John Clader

series ordinal

11

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Lili Zhang

series ordinal

12

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Mary Cohen-Williams

series ordinal

13

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Nicholas Jones

series ordinal

14

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Anandan Palani

series ordinal

16

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

Lynn Hyde

series ordinal

15

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21195610

retrieved

21 November 2024

language of work or name

English

0 references

publication date

13 December 2010

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

full work available at URL

https://api.elsevier.com/content/article/PII:S0960894X1001766X?httpAccept=text/xml

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

https://api.elsevier.com/content/article/PII:S0960894X1001766X?httpAccept=text/plain

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

published in

Bioorganic & Medicinal Chemistry Letters

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

volume

21

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

issue

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

page(s)

664-669

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

cites work

Current approaches in the treatment of Alzheimer's disease

series ordinal

1

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Therapy for Alzheimer's Disease: How Effective are Current Treatments?

series ordinal

3

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Alzheimer's disease: the amyloid cascade hypothesis

series ordinal

4

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

series ordinal

5

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Studies to investigate the in vivo therapeutic window of the gamma-secretase inhibitor N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY411,575) in the CRND8 mouse

series ordinal

8

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42.

series ordinal

12

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

series ordinal

13

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Substrate-targeting gamma-secretase modulators

series ordinal

14

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

At the frontline of Alzheimer's disease treatment: gamma-secretase inhibitor/modulator mechanism

series ordinal

15

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Inhibition and modulation of gamma-secretase for Alzheimer's disease

series ordinal

16

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

series ordinal

17

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

series ordinal

18

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures.

series ordinal

19

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Abeta42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain.

series ordinal

20

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Clinical trial of indomethacin in Alzheimer's disease.

series ordinal

21

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

The role of COX-1 and COX-2 in Alzheimer's disease pathology and the therapeutic potentials of non-steroidal anti-inflammatory drugs.

series ordinal

22

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Cassette-accelerated rapid rat screen: a systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new chemical entities as part of new drug discovery

series ordinal

26

1 reference

stated in

Crossref

DOI

10.1016/J.BMCL.2010.12.012

reference URL

https://api.crossref.org/works/10.1016/J.BMCL.2010.12.012

retrieved

21 November 2024

Identifiers

DOI

10.1016/J.BMCL.2010.12.012

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

PubMed publication ID

21195610

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21195610

retrieved

13 May 2018

reference URL

http://europepmc.org/abstract/MED/21195610

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q53315614&oldid=2277750634"