Pharmacokinetics and biological activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. 1. Dose-dependent tissue distribution and induction of hepatic ethoxyresorufin O-deethylase in rats following a single injection. (Q53043637)

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scientific article published in January 1988

Language	Label	Description	Also known as
English	Pharmacokinetics and biological activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. 1. Dose-dependent tissue distribution and induction of hepatic ethoxyresorufin O-deethylase in rats following a single injection.	scientific article published in January 1988

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

Pharmacokinetics and biological activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. 1. Dose-dependent tissue distribution and induction of hepatic ethoxyresorufin O-deethylase in rats following a single injection. (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

K Abraham

1

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

R Krowke

2

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

D Neubert

3

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

publication date

1 January 1988

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

Archives of Toxicology

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Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

62

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Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

5

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

359-368

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organ specific induction of drug metabolizing enzymes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of a microsomal cytochrome P-448-mediated reaction. Ethoxyresorufin O-de-ethylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the mechanism of absorption and distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue distribution, excretion and biological effects of [14C]tetrachlorodibenzo-p-dioxin in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative determination of cytochrome P-450 in rat liver homogenate

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the mechanism of toxicity of the chlorinated dibenzo-p-dioxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural gene products of the Ah locus. Transcriptional regulation of cytochrome P1-450 and P3-450 mRNA levels by 3-methylcholanthrene

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of solvents and adsorbents on dermal and intestinal absorption of TCDD

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD): Results of a 13-week oral toxicity study in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excretion and tissue distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) effects on hepatic microsomal cytochrome P-448-mediated enzyme activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An alternative 7-ethoxyresorufin O-deethylase activity assay: a continuous visible spectrophotometric method for measurement of cytochrome P-450 monooxygenase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fate of 2,3,7,8-tetrachlorodibenzo-p-dioxin following single and repeated oral doses to the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retention and excretion of 2,3,7,8-tetrachlorodibenzo-p-dioxin by rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ingestion of soil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters hepatic enzyme activities in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of mixed-function oxidase by chronic treatment with 2,3,7,8-tetrachloro-dibenzo-p-dioxin in female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transplacental induction of carcinogen-hydroxylating systems with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic expression of aryl hydrocarbon hydroxylase activity. Induction of monooxygenase activities and cytochrome P1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically "nonresponsive" to other aromatic hydrocarbons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene

1 reference

https://pubmed.ncbi.nlm.nih.gov/3242446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00293624

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/3242446

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